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胃癌圍手術(shù)期營(yíng)養(yǎng)風(fēng)險(xiǎn)和并發(fā)癥影響因素分析

發(fā)布時(shí)間:2018-06-27 09:20

  本文選題:胃癌 + 營(yíng)養(yǎng)風(fēng)險(xiǎn); 參考:《中華腫瘤防治雜志》2017年06期


【摘要】:目的胃癌是最常見的消化道惡性腫瘤,圍手術(shù)期營(yíng)養(yǎng)風(fēng)險(xiǎn)和并發(fā)癥發(fā)生率較高,本研究旨在分析胃癌患者圍手術(shù)期營(yíng)養(yǎng)風(fēng)險(xiǎn)和并發(fā)癥的影響因素。方法收集2011-11-01-2014-11-01山東大學(xué)附屬山東省腫瘤醫(yī)院胃腸外科876例胃癌手術(shù)患者的營(yíng)養(yǎng)風(fēng)險(xiǎn)、營(yíng)養(yǎng)支持和圍手術(shù)期并發(fā)癥等數(shù)據(jù),分析營(yíng)養(yǎng)風(fēng)險(xiǎn)以及并發(fā)癥的相關(guān)因素,進(jìn)一步分析營(yíng)養(yǎng)支持和并發(fā)癥的關(guān)系。結(jié)果(1)有營(yíng)養(yǎng)風(fēng)險(xiǎn)492例,發(fā)生率為56.2%,其中積分3分占27.1%,4~7分占29.1%。單因素分析結(jié)果顯示,年齡、臨床分期、病理鮑曼分型和并發(fā)癥與營(yíng)養(yǎng)風(fēng)險(xiǎn)相關(guān);多因素分析顯示,年齡65歲、病理Ⅲ期和并發(fā)癥是獨(dú)立危險(xiǎn)因素。(2)有并發(fā)癥158例,發(fā)生率為18.0%。單因素分析顯示,年齡、病理分期、鮑曼分型、術(shù)中出血量、ASA評(píng)分、營(yíng)養(yǎng)風(fēng)險(xiǎn)和并發(fā)癥與并發(fā)癥顯著相關(guān);多因素分析顯示,年齡65歲、病理分期Ⅲ期、營(yíng)養(yǎng)風(fēng)險(xiǎn)、ASA評(píng)分和并發(fā)癥是獨(dú)立危險(xiǎn)因素。(3)分層分析顯示,有風(fēng)險(xiǎn)者營(yíng)養(yǎng)支持并發(fā)癥為17.9%,低于無規(guī)范營(yíng)養(yǎng)支持的29.2%,無營(yíng)養(yǎng)風(fēng)險(xiǎn)者營(yíng)養(yǎng)支持對(duì)并發(fā)癥無顯著性影響。結(jié)論影響胃癌營(yíng)養(yǎng)風(fēng)險(xiǎn)和并發(fā)癥的獨(dú)立危險(xiǎn)因素有年齡、病理分期和并發(fā)癥,營(yíng)養(yǎng)風(fēng)險(xiǎn)為并發(fā)癥的獨(dú)立危險(xiǎn)因素,規(guī)范的營(yíng)養(yǎng)支持為營(yíng)養(yǎng)風(fēng)險(xiǎn)者并發(fā)癥的保護(hù)性因素。
[Abstract]:Objective gastric cancer is the most common malignant tumor of digestive tract. The nutritional risk and complication rate of gastric cancer patients during perioperative period are higher. The purpose of this study was to analyze the influencing factors of perioperative nutritional risk and complications in patients with gastric cancer. Methods data of nutritional risk, nutritional support and perioperative complications of 876 patients with gastric cancer in Shandong Cancer Hospital affiliated to Shandong University were collected from 2011-11-01-2014-11-01, and the related factors of nutritional risk and complications were analyzed. To further analyze the relationship between nutritional support and complications. Results (1) there were 492 cases with nutritional risk, the incidence rate was 56.2%, of which the score of 3 points accounted for 27.1% and the score of 4 ~ 7 points accounted for 29.1%. Univariate analysis showed that age, clinical stage, pathological Bowman classification and complications were associated with nutritional risk, multivariate analysis showed that age 65 years old, pathological stage 鈪,

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