本文選題：血細(xì)胞分離機(jī) + 校準(zhǔn)系數(shù)　； 參考：《中國輸血雜志》2017年10期

【摘要】：目的通過比較不同校準(zhǔn)系數(shù)(YSF系數(shù))下Trima Accel型血細(xì)胞分離機(jī)采集的單采血小板Plt含量,探尋該機(jī)器在實(shí)際應(yīng)用中的最適校準(zhǔn)系數(shù)。方法選取Trima Accel型血細(xì)胞分離機(jī),將調(diào)節(jié)不同的優(yōu)化YSF系數(shù)后的機(jī)器作為3個(gè)實(shí)驗(yàn)組,保持原YSF系數(shù)的機(jī)器作為對照組。每臺血細(xì)胞分離機(jī)完成采集110例并記錄每份血小板的Plt檢測值,重量,通過公式計(jì)算得出其實(shí)際血小板含量。將4組數(shù)據(jù)進(jìn)行統(tǒng)計(jì)分析,比較不合格率與高值率,繪制正態(tài)分布曲線,選出最合適的血小板YSF系數(shù)。結(jié)果應(yīng)用完全隨機(jī)設(shè)計(jì)的方差分析得出使用相同YSF系數(shù)的不同機(jī)器之間的差異無統(tǒng)計(jì)學(xué)意義(P0.05);每一實(shí)驗(yàn)組與對照組的參數(shù)設(shè)置對單采血小板Plt含量有顯著影響,二者相比有統(tǒng)計(jì)學(xué)意義(P0.05)。應(yīng)用YSF系數(shù)為0.98的機(jī)器采集出的單采血小板Plt含量為(2.76±0.22)×1011/袋,不合格率為14.55%(16/110),高值率為20.00%(22/110);應(yīng)用YSF系數(shù)為0.99的機(jī)器采集出的單采血小板Plt含量為(2.69±0.18)×1011/袋,不合格率為14.55%(16/110),高值率為12.73%(14/110);應(yīng)用YSF系數(shù)為1.00的機(jī)器采集出的單采血小板Plt含量為(2.65±0.23)×1011/袋,不合格率為22.73%(25/110),高值率為13.64%(15/110);應(yīng)用YSF系數(shù)為1.01的機(jī)器采集出的單采血小板Plt含量為(2.59±0.19)×1011/袋,不合格率為33.64%(37/110),高值率為3.64%(4/110)。再經(jīng)過正態(tài)分布曲線比較后得出的最適YSF系數(shù)為0.99。結(jié)論 Trima Accel型血細(xì)胞分離機(jī)在YSF系數(shù)為0.99時(shí),離散程度最小,合格率符合國家標(biāo)準(zhǔn),高值率處于最佳水平,可優(yōu)化血小板的采集過程,提高血小板單采的綜合質(zhì)量。
[Abstract]:Objective to compare the PLT content of blood platelets collected by Trima Accel blood cell separator under different calibration coefficients (YSF) and to find out the optimal calibration coefficient of the machine in practical application. Methods Trima Accel blood cell separator was selected. The machine after adjusting different optimized YSF coefficients was used as three experimental groups, and the machine maintaining the original YSF coefficient as the control group. Each blood cell separator collected 110 cases and recorded the PLT detection value and weight of each platelet. The actual platelet content was calculated by formula. The four groups of data were statistically analyzed, the unqualified rate and the high value rate were compared, the normal distribution curve was drawn, and the most suitable platelet YSF coefficient was selected. Results the variance analysis of complete random design showed that there was no significant difference between different machines with the same YSF coefficient, and the parameters of each experimental group and control group had a significant effect on platelet Plt content. There was significant difference between the two groups (P 0.05). The PLT content of platelets collected by a machine with YSF coefficient of 0.98 was 2.76 鹵0.22) 脳 1011 / bag, the unqualified rate was 14.55 / 10 / 10 and the high value was 20.00% 22 / 110 / bag, and the Plt content of platelets collected by the machine with 0.99 coefficient of YSF was 2.69 鹵0.18 脳 1011 / bag. The unqualified rate was 14.55 / 110 / 10 and the high value was 12.73 / 110 / 10. The PLT content of platelets collected by the machine with YSF coefficient 1.00 was 2.65 鹵0.23) 脳 1011 / bag, the unqualified rate was 22.73% 25 / 110 and the high value rate was 13.64 / 15 / 110 / bag; the PLT content of single platelet collected by the machine with YSF coefficient 1.01 was 2.59 鹵0.19) 脳 1011 / bag. The failure rate was 33.64 / 110, and the high value was 3.64 / 110. The optimum YSF coefficient is 0.99 after the comparison of normal distribution curves. Conclusion when the coefficient of YSF is 0.99, Trima Accel blood cell separator has the lowest degree of dispersion, the qualified rate is in line with the national standard, and the high value rate is at the best level, which can optimize the process of platelet collection and improve the comprehensive quality of platelet collection.
【作者單位】： 大連市血液中心;
【分類號】：R457.1
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本文編號：1996091