本文選題：肝動脈栓塞化療 + 錐形束CT�。� 參考：《基因組學(xué)與應(yīng)用生物學(xué)》2017年09期

【摘要】：為了深入了解基于CBCT的三維重建技術(shù)在原發(fā)性肝癌TACE治療中的應(yīng)用,本研究對在我院進(jìn)行TACE治療的原發(fā)性肝癌患者,分別采用基于CBCT的三維重建技術(shù)和常規(guī)的DSA技術(shù)進(jìn)行分析比較。我們選取我院2013年1月~2015年10月確診的67例原發(fā)性肝癌患者,采用隨機數(shù)字表法分為CBCT組34例、血管造影(DAS組)33例,兩組均采用TACE治療,術(shù)中分別給予CBCT及三維重建、DSA技術(shù)進(jìn)行手術(shù)指指導(dǎo)。研究表明:CBCT組對腫瘤供血動脈檢出正確率、超選擇動脈插管成功率、碘油在病灶中完全沉積率均高于DSA組(p0.05);CBCT組的手術(shù)時間、輻射總劑量均高于DSA組(p0.05);術(shù)后一個月復(fù)查,CBCT組CR 17.65%、PR 73.53%、SD 8.82%,DSA組CR 6.06%、PR 66.67%、SD 21.21%、PD 6.06%,兩組比較差異具有統(tǒng)計學(xué)意義(p0.05);術(shù)后一個月復(fù)查,CBCT組血清AFP水平低于DSA組(p0.05);兩組患者的KPS評分較本組術(shù)前均顯著的提高(p0.05),兩組間的KPS評分差異無統(tǒng)計學(xué)意義(p0.05)。我們的研究初步得出結(jié)論:基于CBCT的三維重建技術(shù)在原發(fā)性肝癌TACE治療中較DSA技術(shù)能夠更好的檢出腫瘤的供血動脈、指導(dǎo)手術(shù)更加便捷和精確,能達(dá)到更好的手術(shù)效果。
[Abstract]:In order to understand the application of three-dimensional reconstruction technique based on CBCT in the treatment of primary liver cancer (HCC) with TACE, we studied the patients with primary liver cancer treated with TACE in our hospital. Three-dimensional reconstruction technology based on CBCT and conventional DSA technology are used to analyze and compare. From January 2013 to October 2015, 67 patients with primary liver cancer were randomly divided into CBCT group (n = 34) and angiography group (n = 33). Both groups were treated with TACE. CBCT and three-dimensional reconstruction were used to guide the operation. The results showed that the accuracy rate of detecting tumor supplying artery, the success rate of super selective artery intubation, the complete deposition rate of lipiodol in the lesion in the group of 10% CBCT were higher than those in the group of DSA (p 0.05). The total dose of radiation was higher than that of DSA group (P 0.05), and the level of serum AFP in CBCT group was lower than that in DSA group one month after operation. The serum AFP level in CBCT group was lower than that in DSA group (P 0.05). The scores were significantly higher than those before operation (P 0.05). There was no significant difference in KPS score between the two groups (P 0.05). Our preliminary conclusion is that 3D reconstruction based on CBCT can detect the blood supply artery of primary liver cancer better than that of DSA in TACE therapy. It is more convenient and accurate to guide the operation and can achieve better operation effect.
【作者單位】： 河北醫(yī)科大學(xué)第四醫(yī)院放射科;
【基金】：河北醫(yī)科大學(xué)第四醫(yī)院資助
【分類號】：R730.44;R735.7

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本文編號：1962762