發(fā)布時(shí)間：2018-05-09 14:14

  本文選題：釓塞酸二鈉 + 肝臟局灶性結(jié)節(jié)增生　； 參考：《中國(guó)醫(yī)學(xué)計(jì)算機(jī)成像雜志》2017年05期

【摘要】：目的:探討使用Gd-EOB-DTPA增強(qiáng)MRI在肝臟局灶性結(jié)節(jié)增生(FNH)的診斷價(jià)值。方法:進(jìn)行回顧性分析16例經(jīng)病理證實(shí)的FNH的MRI檢查資料,所有病例均行MRI平掃及Gd-EOB-DTPA增強(qiáng)掃描。結(jié)果:16例共20個(gè)病灶,位于肝左葉8個(gè),肝右葉6個(gè),尾狀葉2個(gè),跨葉生長(zhǎng)4個(gè)。MRI特征T1WI 9例呈等信號(hào),7例呈稍低信號(hào),抑脂T2WI 6例呈等信號(hào),10例呈稍高信號(hào);7例病灶見(jiàn)中央瘢痕,呈T1WI低信號(hào),T2WI高信號(hào)。動(dòng)態(tài)增強(qiáng)動(dòng)脈期16例病灶均明顯強(qiáng)化;門脈期持續(xù)強(qiáng)化,12例呈稍高信號(hào),4例呈等信號(hào);平衡期11例呈等信號(hào),5例呈稍高信號(hào);肝細(xì)胞特異期,7例病灶以等信號(hào)為主,9例呈不均勻稍高及等、低混雜信號(hào)。中央瘢痕動(dòng)脈期無(wú)強(qiáng)化,門脈期及平衡期持續(xù)延遲強(qiáng)化,肝細(xì)胞特異期呈低信號(hào)。結(jié)論:使用Gd-EOB-DTPA增強(qiáng)MRI診斷FNH具有很高的敏感性及特異性,FNH對(duì)Gd-EOB-DTPA特異性攝取而呈等、高信號(hào),Gd-EOB-DTPA增強(qiáng)能準(zhǔn)確地顯示FNH的血供特點(diǎn)及病理特征,大大提高與肝內(nèi)其他病變的鑒別診斷能力。
[Abstract]:Objective: to evaluate the diagnostic value of Gd-EOB-DTPA enhanced MRI in focal nodular hyperplasia of liver. Methods: the MRI findings of 16 cases of pathologically proved FNH were retrospectively analyzed. All cases underwent MRI plain scan and Gd-EOB-DTPA enhanced scan. Results there were 20 lesions in 16 cases, including 8 lesions in Zuo Ye, 6 in right lobe, 2 in caudate lobe, and 4 in translobar growth. MRI features of 9 cases showed isokinetic signal intensity in 7 cases and slightly low signal intensity in 7 cases. In 6 cases of lipid-suppressive T2WI, 10 cases showed iso-signal intensity and 10 cases showed slightly hyperintense lesions, 7 cases showed central scar, and showed T1WI low signal intensity on T _ 2WI. In dynamic contrast enhanced arterial phase, 16 lesions were obviously enhanced, 12 cases showed slight hyperintense signal in 12 cases, 11 cases showed isointense signal in 5 cases in equilibrium phase, 12 cases showed slight hyperintense signal in 12 cases, and 5 cases showed slight hyperintense signal in 11 cases in equilibrium phase. In 7 cases of hepatocyte specific phase, iso-signal was the main signal in 9 cases, which showed heterogeneity and homogeneity and low mixed signal. There was no enhancement in the arterial phase of central scar, but delayed enhancement in portal phase and equilibrium phase, and low signal intensity in the specific phase of hepatocyte. Conclusion: Gd-EOB-DTPA enhanced MRI has high sensitivity and specificity in the diagnosis of FNH. Gd-EOB-DTPA enhancement can accurately display the blood supply characteristics and pathological features of FNH. To improve the ability of differential diagnosis with other liver diseases.
【作者單位】： 鄭州市人民醫(yī)院影像科;安陽(yáng)市人民醫(yī)院影像科;
【分類號(hào)】：R445.2;R575

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