某院住院患者肺炎鏈球菌感染與耐藥性研究
發(fā)布時(shí)間:2018-05-09 08:01
本文選題:肺炎鏈球菌 + 耐藥 ; 參考:《中華醫(yī)院感染學(xué)雜志》2017年13期
【摘要】:目的探討醫(yī)院肺炎鏈球菌感染與耐藥性情況,為臨床治療提供指導(dǎo)依據(jù)。方法選取2015年1月-2016年12月于醫(yī)院住院或就診的感染者標(biāo)本8126份,進(jìn)行病原菌菌株鑒定和藥敏試驗(yàn);由專職人員統(tǒng)計(jì)標(biāo)本采集科室、部位及患者年齡、性別等基本信息。結(jié)果 8126份患者標(biāo)本,分離得到肺炎鏈球菌158份,檢出率為1.94%。共檢出病原菌158株,其中痰液檢出125株占79.11%,血液檢出12株占7.59%,胸水檢出8株占5.06%、腦脊液檢出6株占3.80%、膿液檢出4株占2.53%,其他標(biāo)本檢出3株占1.90%;≤3歲患者檢出86株占54.43%,4~15歲患者檢出12株占7.59%,16~40歲患者檢出14株占8.86%,41~60歲患者檢出18株占11.39%,61歲以上患者檢出28株占17.72%;兒科檢出92株,占58.23%,重癥監(jiān)護(hù)室檢出26株占16.46%,呼吸科檢出22株占13.92%,腫瘤科檢出10株占6.33%,其他科室檢出8株占5.06%;2015年檢出69株占43.67%,2016年檢出89株占56.33%。2015年-2016年肺炎鏈球菌耐藥率有上升趨勢;肺炎鏈球菌對青霉素G、紅霉素、克林霉素和四環(huán)素耐藥率均在80%以上,對氯霉素、萬古霉素、利奈唑胺、左氧氟沙星、阿米卡星、頭孢唑林和頭孢噻肟等耐藥率較低,較為敏感。結(jié)論嬰幼兒是肺炎鏈球菌感染的高危人群,且肺炎鏈球菌耐藥率呈上升趨勢。
[Abstract]:Objective to explore the situation of nosocomial streptococcus pneumoniae infection and drug resistance in order to provide guidance for clinical treatment. Methods from January 2015 to December 2016, 8126 infected specimens were selected for identification of pathogenic strains and drug susceptibility tests, and basic information such as department, location, patient age, sex and so on were collected by professional staff. Results among 8126 specimens, 158 strains of Streptococcus pneumoniae were isolated and the detection rate was 1.94%. 158 strains of pathogenic bacteria were detected. Among them, 125 strains were detected in sputum, 12 in blood, 5.06 in pleural fluid, 6 in cerebrospinal fluid, 2.53 in pus, 3 in other specimens, 86 in patients with 鈮,
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