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急診重癥監(jiān)護病房多藥耐藥菌監(jiān)測與感染危險因素分析

發(fā)布時間:2018-05-05 21:35

  本文選題:急診重癥監(jiān)護室 + 多藥耐藥菌監(jiān)測; 參考:《中華醫(yī)院感染學(xué)雜志》2017年20期


【摘要】:目的分析急診重癥監(jiān)護病房(EICU)多藥耐藥菌的分布及感染危險因素。方法回顧性調(diào)查2016年1月-12月醫(yī)院88例EICU住院患者的臨床資料,比較多藥耐藥組42例患者和非多藥耐藥組46例患者的差異,分析多藥耐藥菌的分布特征,對多藥耐藥菌感染相關(guān)因素進行分析。結(jié)果共檢出多藥耐藥致病菌42株,多藥耐藥菌依次為耐碳青霉烯類抗菌藥物鮑氏不動桿菌(CR-AB)32株占76.19%、耐甲氧西林金黃色葡萄球菌(MRSA)5株占11.90%、耐碳青霉烯類抗菌藥物腸桿菌科細菌(CRE)3株占7.14%;CR-AB對頭孢哌酮/舒巴坦、替加環(huán)素的耐藥率分別為18.75%、0.00%,MRSA對替加環(huán)素的耐藥率為0.00%,MDR-PA對頭孢哌酮/舒巴坦、哌拉西林/他唑巴坦、亞胺培南、替加環(huán)素耐藥率為0.00%;住院時間14d、抗菌藥物使用時間3d、中心靜脈置管、氣管插管、留置導(dǎo)尿管或胃管、機械通氣時間≥2d均為EICU患者多藥耐藥菌感染相關(guān)的獨立危險因素(P0.05)。結(jié)論 EICU患者多藥耐藥菌感染是多因素共同引起的結(jié)果,臨床應(yīng)針對性采取綜合有效措施,降低EICU患者多藥耐藥菌感染,阻斷多藥耐藥菌的傳播。
[Abstract]:Objective to analyze the distribution of multidrug resistant bacteria in emergency intensive care unit (EICU) and the risk factors of infection. Methods the clinical data of 88 patients with EICU in hospital from January to December 2016 were retrospectively investigated. The differences between 42 patients in multidrug resistance group and 46 patients in non-multidrug resistance group were compared, and the distribution characteristics of multidrug resistance bacteria were analyzed. The related factors of multidrug resistant bacteria infection were analyzed. Results A total of 42 strains of multidrug resistant pathogens were detected. The multidrug resistant strains were carbapenem resistant Acinetobacter baumannii 32 strains (76.19%), methicillin-resistant Staphylococcus aureus 5 strains (11.90%) and carbapenem resistant Enterobacteriaceae strains (7.14 CR-AB) to cefoperazone / sulbactam (7.14 CR-AB). The resistance rates of tegicycline to tegacycline were 18.75 and 0.0075 respectively. The resistance rate of MRSA to tegacyclin was 0.005. The MDR-PA resistance rate was 0.005% to cefoperazone / sulbactam, piperacillin / tazobactam, imipenem, piperacillin / tazobactam, and imipenem, respectively. The rate of tegacycline resistance was 0.00g, the hospitalization time was 14 days, the use time of antimicrobial agents was 3 days, the central venous catheter, tracheal intubation, indwelling catheter or gastric tube, the mechanical ventilation time 鈮,

本文編號:1849389

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