本文選題：血流感染 + 血培養(yǎng)��； 參考：《中國感染控制雜志》2017年03期

【摘要】：目的了解三亞地區(qū)某醫(yī)院血流感染病原菌分布及其耐藥情況。方法回顧性分析該院2013年1月—2015年12月臨床送檢血培養(yǎng)標(biāo)本及藥敏試驗結(jié)果。結(jié)果 3 195份血培養(yǎng)標(biāo)本共檢出陽性病原菌356株,陽性率為11.14%,其中革蘭陰性菌215株(占60.39%),革蘭陽性菌122株(占34.27%),真菌19株(占5.34%)。革蘭陰性菌分離菌株數(shù)較多的是大腸埃希菌(90株,25.28%)、肺炎克雷伯菌(60株,16.85%)及假鼻疽伯克霍爾德菌(24株,6.74%);革蘭陽性菌則以金黃色葡萄球菌(42株,11.80%)、凝固酶陰性葡萄球菌(38株,10.67%)及鏈球菌屬細菌(33株,9.27%)居多。大腸埃希菌及肺炎克雷伯菌對頭孢哌酮/舒巴坦、阿米卡星及碳青霉烯類耐藥率低于10.00%。假鼻疽伯克霍爾德菌對多數(shù)抗菌藥物的耐藥率低于10.00%。主要革蘭陽性菌未檢測出耐利奈唑胺及萬古霉素的菌株。結(jié)論近期該院血流感染病原菌以革蘭陰性菌為主,尤其假鼻疽伯克霍爾德菌的分離率較其他地區(qū)高,應(yīng)引起臨床重視。
[Abstract]:Objective to investigate the distribution and drug resistance of pathogenic bacteria of blood stream infection in a hospital in Sanya area.Methods the results of clinical blood culture and drug sensitivity test from January 2013 to December 2015 were analyzed retrospectively.Results 356 strains of pathogenic bacteria were detected in 3 195 blood samples, the positive rate was 11.14%, among which 215 strains were Gram-negative bacteria (60.39%), 122 strains were Gram-positive bacteria (34.27%), 19 strains were fungi (5.34%).Gram-negative bacteria isolated were Escherichia coli 90 strains 25.28%, Klebsiella pneumoniae 60 strains 16.85) and Bacillus pseudorrhoeae 24 strains 6.740.Gram-positive bacteria consisted of 42 strains of Staphylococcus aureus 11.80% and coagulase-negative staphylococcus.And 33 strains of Streptococcus spp.The resistance rates of Escherichia coli and Klebsiella pneumoniae to cefoperazone / sulbactam, amikacin and carbapenes were lower than 10.00.The resistance to most antimicrobial agents was lower than 10.00.The main gram-positive strains were not resistant to linazolamine and vancomycin.Conclusion Gram-negative bacteria are the main pathogens of blood flow infection in this hospital recently, especially the isolation rate of Burkholderia pseudorhini is higher than that in other areas, which should be paid more attention to in clinic.
【作者單位】： 海南省第三人民醫(yī)院;海南醫(yī)學(xué)院;中南大學(xué)湘雅三醫(yī)院醫(yī)學(xué)實驗中心;
【基金】：海南省三亞市醫(yī)療衛(wèi)生科技創(chuàng)新基金資助項目(2014YW23)
【分類號】：R197.323;R446.5

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