發(fā)布時(shí)間：2018-03-20 15:05

  本文選題：中心靜脈導(dǎo)管相關(guān)血流感染　切入點(diǎn)：重癥監(jiān)護(hù)病房　出處：《中國感染控制雜志》2017年04期 　論文類型：期刊論文

【摘要】：目的了解重癥兒童中心靜脈導(dǎo)管相關(guān)血流感染(CLABSI)發(fā)病情況,為制定防控措施提供依據(jù)。方法采用前瞻性目標(biāo)監(jiān)測方法,監(jiān)測2012年1月—2015年12月7個(gè)兒童及新生兒重癥監(jiān)護(hù)病房(ICU)中心靜脈置管患者CLABSI情況。結(jié)果共有37 712例患者住院,總住院日為268 531 d,中心靜脈置管日數(shù)為57 639 d,中心靜脈導(dǎo)管使用率為21.46%;126例患者發(fā)生CLABSI,CLABSI發(fā)病率為2.19/1 000插管日,各年度CLABSI發(fā)病率比較,差異無統(tǒng)計(jì)學(xué)意義(P0.05);第三季度CLABSI發(fā)病率高于其他季度[均P0.05,其中與第1季度比較,RR(95%CI)=1.98(1.20,3.29)];不同類型ICU的CLABSI發(fā)病率不同,新生兒外科ICU(SNICU)發(fā)病率(6.12/1 000插管日)高于其他類型ICU[均P0.05,其中與兒童ICU比較,RR(95%CI)=3.02(1.51~6.04)]。126例CLABSI患者共分離病原菌139株,主要病原菌為肺炎克雷伯菌(20.86%)和表皮葡萄球菌(15.83%)。結(jié)論外科重癥新生兒是CLABSI感染的高危人群,應(yīng)針對該科室制定強(qiáng)化措施進(jìn)行干預(yù),才能有效降低CLABSI。
[Abstract]:Objective to investigate the incidence of CLABSIin the central venous catheter associated blood flow infection in severe children, and to provide the basis for the prevention and control measures. From January 2012 to December 2015, the CLABSI of 7 patients with central venous catheterization in children and neonatal intensive care unit (NICU) were monitored. Results A total of 37 712 patients were hospitalized. The total hospitalization days were 268,531 days, the number of central venous catheterization days was 57,639 days, the utilization rate of central venous catheters was 21.46 and the incidence of CLABSICLABSI was 2.19 / 1 000 intubation days. The incidence of CLABSI in each year was compared. The incidence of CLABSI in the third quarter was higher than that in the other quarters (P0.05, respectively, compared with the first quarter). The incidence of CLABSI in different types of ICU was different. The incidence of ICU in neonatal surgery was 6.12 / 1 000 intubation days), which was higher than that of other types of ICU (all P 0.05, including 3.02% 1.51% 6.04 in comparison with ICU in children). 139 strains of pathogenic bacteria were isolated from 126 patients with CLABSI. The main pathogenic bacteria were Klebsiella pneumoniae 20.86) and Staphylococcus epidermidis 15.83.Conclusion the severe surgical newborns are the high risk population of CLABSI infection.
【作者單位】： 廣州市婦女兒童醫(yī)療中心;
【基金】：廣東省科技計(jì)劃項(xiàng)目(2012B061700011) 廣州市科技計(jì)劃項(xiàng)目(2014Y2-00031)
【分類號】：R473.72

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