本文選題：肝母細胞瘤　切入點：體層攝影術　出處：《生物醫(yī)學工程與臨床》2017年03期 　論文類型：期刊論文

【摘要】：目的基于肝母細胞瘤PRETEXT分期系統(tǒng)及其相關影像學高危預后因素,總結(jié)肝母細胞瘤影像學表現(xiàn)。方法選擇2013年1月至2015年6月在首都兒科研究所附屬兒童醫(yī)院經(jīng)手術和病理確診的肝母細胞瘤CT影像學資料82例,其中男性42例,女性40例;年齡1個月~11歲,平均年齡1.65歲。觀察腫瘤位置、大小、數(shù)量、邊界、腫瘤內(nèi)壞死及鈣化等征象;此外,基于PRETEXT分期,探討與預后相關的高危影像學征象(腫瘤侵襲鄰近器官、腹水、腫瘤破裂出血、遠處器官轉(zhuǎn)移、淋巴結(jié)轉(zhuǎn)移、肝靜脈受累、門靜脈/下腔靜脈受累等)關系。結(jié)果 PRETEXT分期Ⅰ期5例,Ⅱ期38例,Ⅲ期33例,Ⅳ期6例。腫瘤的CT表現(xiàn),39例(47.6%)在右葉,22例(26.8%)在左右葉,18例(22.0%)在左葉,3例(3.6%)在尾葉。腫瘤體積約為2.5 cm×2.5 cm×3.0 cm~9.2 cm×18.6 cm×20.0 cm。71例(86.6%)腫瘤單發(fā),11例(13.4%)腫瘤多發(fā)。64例(78.0%)腫瘤與肝臟實質(zhì)多數(shù)分界清楚,18例(22.0%)邊界模糊。腫瘤內(nèi)壞死:72例(87.8%)有大小不等、分布無規(guī)律、數(shù)量不定的裂隙狀或片狀低密度區(qū)(CT值約15~38 Hu)。49例(59.8%)有點片狀、團塊狀和多種形態(tài)混合狀的鈣化。高危預后因素最常見為遠處轉(zhuǎn)移33例(40.2%),以肺轉(zhuǎn)移多見;其次是門靜脈主干、三支肝靜脈或下腔靜脈受累13(15.9%)、PRETEXTⅣ期6例(7.3%)、淋巴結(jié)轉(zhuǎn)移5例(6.1%),腫瘤肝外腹部侵襲(0例)及腫瘤破裂出血(0例)相對少見。結(jié)論肝母細胞瘤的術前增強CT檢查可著重觀察與臨床分期及高危預后相關征象,有助于臨床分期、治療和預后的判斷。
[Abstract]:Objective based on the PRETEXT staging system of hepatoblastoma and its associated imaging high risk prognostic factors. Methods from January 2013 to June 2015, 82 patients (42 males and 40 females) with hepatoblastoma confirmed by operation and pathology were selected from the Children's Hospital affiliated to Capital Institute of Pediatrics. The age ranged from 1 month to 11 years, with an average age of 1.65 years. The location, size, number, boundary, necrosis and calcification of the tumor were observed. In addition, based on the PRETEXT staging, the prognostic high risk imaging signs (invasion of adjacent organs) were investigated. Ascites, tumor rupture and hemorrhage, distant organ metastasis, lymph node metastasis, hepatic vein involvement, portal vein / inferior vena cava involvement, etc. Stage 鈪，

本文編號：1632899