本文選題：多發(fā)性骨髓瘤　切入點(diǎn)：磁共振成像　出處：《中國醫(yī)學(xué)影像學(xué)雜志》2017年11期 　論文類型：期刊論文

【摘要】：目的探討全身磁共振成像(WB-MRI)中多發(fā)性骨髓瘤(MM)病灶浸潤類型評估患者預(yù)后的價值。資料與方法選擇2010年1月—2016年12月經(jīng)病理證實(shí)的62例MM患者,行WB-MRI檢查前均未進(jìn)行治療,將患者WB-MRI病灶浸潤類型分為正常型、小結(jié)節(jié)型、大結(jié)節(jié)型、混合型、彌漫型,比較不同病灶浸潤類型對患者總生存期的影響。結(jié)果 62例患者中,正常型5例,小結(jié)節(jié)型20例,大結(jié)節(jié)型13例,混合型7例,彌漫型17例。所有患者均隨訪30.9~47.1個月,中位隨訪時間39個月,混合型患者的中位總生存期為17.0個月(95%CI 12.6~21.3個月),明顯比其他浸潤類型患者的中位總生存期43.0個月短(95%CI 33.7~52.3個月),差異有統(tǒng)計(jì)學(xué)意義(P0.05)。此外,按DS和ISS分期系統(tǒng)評估初診患者的腫瘤臨床分期,其中DS I期6例,Ⅱ期6例,Ⅲ期50例;ISSⅠ期15例,Ⅱ期22例,Ⅲ期25例,WB-MRI病灶浸潤類型與臨床DS分期、ISS分期間無顯著相關(guān)(P0.05)。結(jié)論 WB-MRI中MM的不同浸潤類型對評估患者預(yù)后有重要價值。
[Abstract]:Objective to evaluate the prognosis of patients with multiple myeloma (MM) lesions in WB-MRI. Materials and methods 62 patients with MM confirmed by pathology from January 2010 to 2016 were selected and none of them were treated before WB-MRI. Patients with WB-MRI were divided into normal type, small nodular type, large nodular type, mixed type and diffuse type. There were 13 cases of large nodular type, 7 cases of mixed type and 17 cases of diffuse type. All the patients were followed up for 30.9 ~ 47.1 months, with a median follow-up time of 39 months. The median total survival time of patients with mixed type was 17.0 months, 95 CI 12.6U 21.3 months, which was significantly shorter than that of other infiltrating patients with 43.0 months CI 33.7 ~ 52.3 months, and the difference was statistically significant (P 0.05). According to DS and ISS staging system, the clinical staging of newly diagnosed patients was evaluated, including 6 cases of DS stage I, 6 cases of stage 鈪，

本文編號：1608592