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定量CT與MR mDixon-quant測量肝臟脂肪含量的相關(guān)性研究

發(fā)布時間:2018-03-04 21:07

  本文選題:肝臟脂肪含量 切入點:定量CT 出處:《放射學實踐》2017年05期  論文類型:期刊論文


【摘要】:目的:比較、分析定量CT(QCT)和MR mDixon-quant對健康人群肝臟脂肪含量測量結(jié)果的一致性和相關(guān)性。方法:對21位男性和32位女性健康社區(qū)居民進行腹部QCT和MR mDixon-quant掃描,QCT分別采用標準計算公式(測量結(jié)果記為Fat%QI)和校正后的計算公式(測量結(jié)果記為Fat%QR)測量肝臟脂肪含量,并采用MR mDixon-quant測量肝臟脂肪分數(shù)(測量結(jié)果記為Fat%mD)。比較男、女兩組之間的肝臟脂肪含量的測量結(jié)果有無差異,比較總體樣本QCT與MR mDixon-quant測量結(jié)果之間的一致性,并計算相關(guān)性系數(shù)。結(jié)果:QCT及MR mDixon-quant的測量結(jié)果均顯示,男性與女性的肝臟脂肪含量差異均無統(tǒng)計學意義(P值均0.05)?傮w樣本的Fat%QI和Fat%QR分別為(-0.09%±4.88%)和(8.66%±4.41%),Fat%QI顯著低于Fat%mD(P0.01),平均差值為(-6.42%±2.44%),而Fat%QR顯著高于Fat%mD(P0.01),平均差值為(2.33%±2.36%)。Fat%QI、Fat%mD的相關(guān)程度(r=0.708,P0.01)與Fat%QR、Fat%mD的相關(guān)程度(r=0.707,P0.01)近似。結(jié)論:與MR mDixon-quant的測量結(jié)果相比,使用重新校正的計算公式的QCT能夠準確測量中國健康人群的肝臟脂肪含量。
[Abstract]:Objective: to compare, To analyze the consistency and correlation between quantitative CTT and Mr mDixon-quant in measuring liver fat content in healthy people. Methods: 21 male and 32 female healthy community residents were performed abdominal QCT and Mr mDixon-quant scanning QCT with standard calculation, respectively. The formula (the measured result is FatQI) and the corrected formula (the measured result is Fatkyam QR) to measure the fat content of the liver, Mr mDixon-quant was used to measure hepatic fat fraction (the result was recorded as Fatma DX). The difference of liver fat content between male and female groups was compared, and the consistency between QCT and Mr mDixon-quant was compared between the two groups. The correlation coefficient was calculated. Results both the measurement results of QCT and Mr mDixon-quant showed that, There was no significant difference in liver fat content between male and female. The Fat%QI and Fat%QR of the total sample were -0.09% 鹵4.88g) and 8.66% 鹵4.41% respectively. The average difference was -6.42% 鹵2.44%, and the average difference was -6.42% 鹵2.44%. The average difference was 2.33% 鹵2.36% 鹵2.36%. The degree of correlation between QR and FatmD is approximately 0.707 / P0.01.Conclusion: compared with the results of Mr mDixon-quant, QCT using the revised formula can accurately measure liver fat levels in healthy Chinese people.
【作者單位】: 北京積水潭醫(yī)院放射科;Biomedical
【基金】:國家自然科學基金青年項目81401407
【分類號】:R445.2;R575;R816.5

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