腦膜瘤中ADC值、rADC值與Ki-67增殖指數(shù)的相關(guān)性分析
發(fā)布時(shí)間:2018-01-07 03:18
本文關(guān)鍵詞:腦膜瘤中ADC值、rADC值與Ki-67增殖指數(shù)的相關(guān)性分析 出處:《臨床放射學(xué)雜志》2017年01期 論文類型:期刊論文
更多相關(guān)文章: 腦膜瘤 擴(kuò)散加權(quán)成像 Ki-增殖指數(shù)
【摘要】:目的探討腦膜瘤的表觀擴(kuò)散系數(shù)(ADC)值、相對(duì)表觀擴(kuò)散系數(shù)(rADC)值與Ki-67增殖指數(shù)的相關(guān)性,提高術(shù)前評(píng)估腦膜瘤復(fù)發(fā)風(fēng)險(xiǎn)的準(zhǔn)確率。方法回顧性分析經(jīng)病理證實(shí)且行Ki-67陽(yáng)性率測(cè)定的47例腦膜瘤患者資料,術(shù)前均行常規(guī)MRI及DWI檢查,測(cè)量腫瘤實(shí)質(zhì)、腫瘤實(shí)質(zhì)對(duì)側(cè)鏡面正常區(qū)的ADC及ADCwm值,計(jì)算rADC值(ADC/ADC_(wm))并分析ADC、rADC與Ki-67增殖指數(shù)的相關(guān)性。結(jié)果腦膜瘤的ADC值與Ki-67增殖指數(shù)呈負(fù)相關(guān)(r~2=0.33,P0.001),rADC值與Ki-67增殖指數(shù)也呈負(fù)相關(guān)(r~2=0.31,P0.001)。結(jié)論 ADC值、rADC值與Ki-67增殖指數(shù)的負(fù)相關(guān)關(guān)系對(duì)術(shù)前明確腦膜瘤的病理級(jí)別及手術(shù)方式的選擇很有價(jià)值。
[Abstract]:Objective To investigate the correlation between the value of apparent diffusion coefficient ( ADC ) and the value of apparent diffusion coefficient ( rADC ) and Ki - 67 proliferation index , and to improve the accuracy of preoperative evaluation of the risk of recurrence . The correlation between ADC value and Ki - 67 proliferation index was analyzed retrospectively . Results The ADC value was negatively correlated with Ki - 67 proliferation index ( r ~ 2 = 0.33 , P0.001 ) , and the rADC value was negatively correlated with Ki - 67 proliferation index ( r ~ 2 = 0.31 , P 0.001 ) . Conclusion The negative correlation between ADC value , rADC value and Ki - 67 proliferation index is valuable for the preoperative diagnosis of the pathological grade and surgical mode .
【作者單位】: 濰坊醫(yī)學(xué)院醫(yī)學(xué)影像學(xué)系;濰坊市人民醫(yī)院放射科;濰坊市人民醫(yī)院病理科;
【分類號(hào)】:R739.45;R445.2
【正文快照】: 腦膜瘤是最常見(jiàn)的腦膜起源腫瘤,占成人顱內(nèi)腫瘤的35%[1]。大多數(shù)(90%)為低級(jí)別腦膜瘤,少數(shù)為高級(jí)別腦膜瘤。高級(jí)別腦膜瘤比低級(jí)別腦膜瘤有更高的復(fù)發(fā)風(fēng)險(xiǎn)。本研究探討腦膜瘤表觀擴(kuò)散系數(shù)(ADC)、相對(duì)表觀擴(kuò)散系數(shù)(rA DC)與Ki-67增殖指數(shù)的相關(guān)關(guān)系,以期提高術(shù)前評(píng)估腦膜瘤復(fù)發(fā)
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