本文關(guān)鍵詞：膿毒癥患者血清氨基酸末端B型利鈉肽前體和心肌酶水平及臨床意義　出處：《中國(guó)老年學(xué)雜志》2017年01期 　論文類型：期刊論文

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【摘要】：目的檢測(cè)膿毒癥患者血清中氨基酸末端B型利鈉肽前體(NT-pro BNP)和心肌酶的水平,分析其臨床意義。方法膿毒癥患者72例作為觀察組,同期體檢未見(jiàn)明顯器質(zhì)性疾病的成人25例血清標(biāo)本作為對(duì)照組。檢測(cè)兩組中NT-pro BNP、谷草轉(zhuǎn)氨酶(AST)、乳酸脫氫酶(LDH)、磷酸肌酸激酶(CK)、磷酸肌酸激酶同工酶(CK-MB)的水平。結(jié)果觀察組血清中NT-pro BNP、AST、LDH、CK、CK-MB的水平均明顯高于對(duì)照組。觀察組中NT-pro BNP、AST、LDH、CK、CK-MB的水平與患者的預(yù)后密切相關(guān),相關(guān)分析顯示急性生理與慢性健康(APACHE)Ⅱ評(píng)分均與NT-pro BNP、AST、LDH、CK、CK-MB的水平呈正相關(guān)性。結(jié)論膿毒癥患者NT-pro BNP和心肌酶各指標(biāo)的表達(dá)均升高,其不僅促進(jìn)病變的進(jìn)展,還對(duì)判斷病變的嚴(yán)重程度及預(yù)后有一定價(jià)值。
[Abstract]:Objective to detect the levels of NT-pro BNPs and myocardial enzymes in serum of sepsis patients. Methods 72 patients with sepsis were treated as observation group. At the same time, the serum samples of 25 adults with no obvious organic diseases were used as control group. NT-pro, aspartate aminotransferase and lactate dehydrogenase were detected in the two groups. Results the serum levels of creatine phosphokinase (CK) and creatine phosphokinase isoenzyme (CK-MBB) were measured. The levels of CK-MB were significantly higher than those of the control group. The level of CK-MB in the NT-pro BNPN ASTN was closely related to the prognosis of the patients. Correlation analysis showed that both acute physiological and chronic health Apache 鈪，

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