本文關(guān)鍵詞：2013-2014年圍產(chǎn)期孕婦攜帶B族鏈球菌的血清型與耐藥分析　出處：《中國感染與化療雜志》2017年05期 　論文類型：期刊論文

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【摘要】：目的對圍產(chǎn)期孕婦B族鏈球菌(GBS)攜帶株的血清型及藥敏結(jié)果進行分析。方法收集妊娠35~37周孕婦的陰道和直腸分泌物標本,進行細菌培養(yǎng)和鑒定,并統(tǒng)計其陽性率。采用凝集法進行血清學分型,用紙片擴散法進行藥敏試驗,參照2009版CLSI標準判定藥敏結(jié)果,采用WHONET 5.6軟件進行統(tǒng)計分析。結(jié)果 2 533例圍產(chǎn)期孕婦進行GBS的檢測,檢出GBS 264株,陽性率10.4%(264/2 533)。并對153株菌進行了血清分型,其中Ⅲ型占54.9%(84/153)、Ⅰa型占17.6%(27/153)、Ⅰb型占13.1%(20/153);藥敏試驗顯示:該菌對青霉素、頭孢曲松、萬古霉素均敏感,對左氧氟沙星、紅霉素和克林霉素的耐藥率分別是32.9%、68.1%和62.1%;對不同血清型的耐藥情況分析發(fā)現(xiàn),Ⅲ型菌株對以上3種藥物的耐藥率明顯高于其他血清型菌株。結(jié)論孕婦陰道和直腸均為GBS的定植部位,建議應對孕婦的陰道和直腸分泌物同時送檢以提高其檢出率;Ⅲ型是GBS主要的血清型;青霉素仍可作為孕產(chǎn)婦及新生兒治療GBS感染的首選藥物,GBS陽性的孕產(chǎn)婦應立即進行干預治療,以保證圍產(chǎn)兒健康。
[Abstract]:Objective to analyze the serotype and drug sensitivity of group B streptococcus B carrying strain in perinatal period. Methods the vaginal and rectal secretions of pregnant women at 3537 weeks of gestation were collected. The bacteria were cultured and identified, and the positive rate was counted. The serological typing was carried out by agglutination method, the drug sensitivity test was carried out by disk diffusion method, and the drug sensitivity results were determined by referring to the 2009 CLSI standard. Results 2 533 cases of perinatal pregnant women were tested for GBS and 264 strains of GBS were detected. The positive rate was 10.4 / 264 / 25330.The serotyping of 153 strains of bacteria was carried out, of which type 鈪，

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