本文選題：子宮收縮(UC)　切入點：胎心率(FHR)　出處：《杭州電子科技大學》2017年碩士論文

【摘要】：子宮收縮和胎兒心率是孕期重要的生理特征,同時也是非常重要的臨床產(chǎn)檢參數(shù)。臨床上宮縮和胎心率異常往往是早產(chǎn)或是流產(chǎn)的先兆病癥,通過對宮縮和胎心率進行持續(xù)性監(jiān)測能夠及時地發(fā)現(xiàn)孕婦和胎兒存在的危險,達到預防早產(chǎn)或流產(chǎn)的目的。隨著科技的發(fā)展,人們對醫(yī)療服務水平提出了更高的要求,孕婦希望醫(yī)療監(jiān)護能夠更加便捷,能夠?qū)崿F(xiàn)實時地監(jiān)護胎兒的健康情況,移動互聯(lián)網(wǎng)技術(shù)和醫(yī)療技術(shù)的結(jié)合為這種居家監(jiān)護模式帶來了可能。本文針對孕婦監(jiān)測宮縮和胎心率以確認胎兒是否處于正常狀態(tài)的剛性需求,設計并實現(xiàn)了一套更加便攜式的居家的可持續(xù)監(jiān)控胎心率和宮縮信號的監(jiān)護系統(tǒng),由智能硬件監(jiān)測終端、客戶端APP、Web服務器端等部分組成。本文重點設計開發(fā)了智能硬件監(jiān)測終端,能夠進行宮縮和胎心率數(shù)據(jù)處理與算法分析,實現(xiàn)實時居家監(jiān)測功能。同時還設計開發(fā)了配套的客戶端APP和Web服務器,能夠顯示宮縮壓力和胎心率曲線產(chǎn)檢圖,進行云端數(shù)據(jù)共享等。本文主要完成了如下幾個方面的內(nèi)容:(1)硬件終端電路設計:設計實現(xiàn)了可靠的硬件電路,主要包括宮縮壓力和胎心信號采集與預處理電路、MSP430MCU核心控制電路、藍牙無線傳輸電路、FLASH存儲電路、電源管理電路、顯示和語音提醒電路等,降低了信號干擾,實現(xiàn)了可靠信號的采集和預處理。(2)基于MSP430MCU硬件終端程序設計:實現(xiàn)了硬件終端的監(jiān)護功能,重點設計實現(xiàn)了宮縮處理算法和胎心率處理算法,形成了宮縮監(jiān)測和胎心監(jiān)測兩個功能子模塊。此外還設計了工作模式控制模塊、數(shù)據(jù)存儲與處理模塊、數(shù)據(jù)無線發(fā)送模塊、提示報警模塊、低功耗控制模塊等,實現(xiàn)了宮縮和胎心數(shù)據(jù)的分析,存儲,處理,診斷結(jié)果提示。(3)客戶端與服務器端功能設計:客戶端主要開發(fā)了監(jiān)測主界面模塊、監(jiān)測數(shù)據(jù)記錄與上傳模塊、個人中心管理模塊等,實現(xiàn)產(chǎn)檢圖的顯示,監(jiān)測記錄保存上傳,生成產(chǎn)檢報告等。Web服務器端主要設計了登錄管理模塊、數(shù)據(jù)保存模塊、產(chǎn)檢圖模塊等,實現(xiàn)了云端數(shù)據(jù)管理,數(shù)據(jù)保存,宮縮壓力曲線和胎心率曲線顯示,監(jiān)測數(shù)據(jù)結(jié)果查詢。(4)系統(tǒng)功能驗證與臨床測試設計:針對系統(tǒng)各個功能模塊,設計了相應的驗證試驗,實現(xiàn)了對硬件終端、客戶端APP及Web服務器端功能的可靠性測試。利用臨床數(shù)據(jù),在Visual C++2010和Matlab平臺上進行了大量的測試和仿真實驗,不斷優(yōu)化核心處理算法,保證了系統(tǒng)診斷結(jié)果的準確性。與合作醫(yī)院進行了多次的臨床測試,不斷改進系統(tǒng),使系統(tǒng)更具臨床實用性。本文所設計的基于智能手機的掌上型孕婦居家監(jiān)護系統(tǒng),能夠使孕婦在家實時地持續(xù)性地監(jiān)測宮縮和胎心率,并參考臨床標準給出診斷結(jié)果,使孕婦可以隨時了解自身和胎兒健康狀況;同時還能夠與合作醫(yī)療機構(gòu)進行數(shù)據(jù)共享,對異常情況進一步診斷,真正實現(xiàn)“產(chǎn)檢搬回家”的理念。
[Abstract]:Uterine contraction and fetal heart rate are important physiological characteristics during pregnancy, and they are also very important parameters of clinical birth examination. Clinically, uterine contraction and abnormal fetal heart rate are often the symptoms of premature delivery or miscarriage. Through continuous monitoring of uterine contraction and fetal heart rate, the risks of pregnant women and fetuses can be detected in time, and the purpose of preventing premature birth or abortion can be achieved. With the development of science and technology, people have put forward higher demands on the level of medical services. Pregnant women hope that medical monitoring can be more convenient and that the health of the fetus can be monitored in real time. The combination of mobile Internet technology and medical technology has made it possible to monitor uterine contractions and heart rates in order to determine whether the fetus is in a normal state. A more portable and sustainable monitoring system of fetal heart rate and uterine contraction signal is designed and implemented, which is monitored by intelligent hardware. This paper focuses on the design and development of intelligent hardware monitoring terminal, which can process and analyze the data of uterine contraction and fetal heart rate. At the same time, the client APP and Web server are designed and developed, which can display contractive pressure and fetal heart rate curve. In this paper, the following aspects of the content of the hardware terminal circuit design: design and implementation of reliable hardware circuit, It mainly includes uterine contraction pressure and fetal heart signal acquisition and preprocessing circuit, MSP430 MCU core control circuit, Bluetooth wireless transmission circuit flash storage circuit, power management circuit, display and voice warning circuit, etc. The acquisition and preprocessing of reliable signal is realized. The program of hardware terminal based on MSP430MCU is designed. The monitoring function of hardware terminal is realized, especially the algorithm of uterine contraction processing and fetal heart rate processing is designed. Two functional sub-modules, uterine contraction monitoring and fetal heart monitoring, are formed. In addition, a working mode control module, a data storage and processing module, a data wireless transmission module, an alarm module and a low-power control module are also designed. The function design of client and server is realized: monitoring main interface module, monitoring data recording and uploading module, monitoring data recording and uploading module are developed in client. The personal center management module and so on, realizes the display of the birth inspection map, the monitoring record keeping and uploading, and so on. Web server mainly designs the login management module, the data preservation module, the birth inspection chart module and so on, realizes the cloud data management, etc. Data preservation, systolic pressure curve and fetal heart rate curve display, monitoring data results query. 4) system function verification and clinical test design: for each functional module of the system, designed the corresponding verification test, realized the hardware terminal, Using clinical data, a large number of tests and simulation experiments have been carried out on the platform of Visual C 2010 and Matlab to optimize the core processing algorithm. The system has been tested many times with the cooperative hospital, and the system has been improved to make the system more practical. In this paper, a hand-held home monitoring system for pregnant women based on smart phone is designed. It enables pregnant women to monitor contractions and heart rates at home in real time and continuously, and provides diagnostic results with reference to clinical criteria, enabling pregnant women to keep abreast of their own and fetal health status, and to share data with cooperative medical institutions. Further diagnosis of abnormal conditions, the real realization of "birth inspection move home" concept.
【學位授予單位】：杭州電子科技大學
【學位級別】：碩士
【學位授予年份】：2017
【分類號】：TP311.56;TP274

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