本文關(guān)鍵詞：光纖分導(dǎo)微梁陣列生化傳感裝置研制及檢測(cè)應(yīng)用　出處：《分析化學(xué)》2017年01期 　論文類型：期刊論文

  更多相關(guān)文章： 生物化學(xué)傳感器 光導(dǎo)纖維 懸臂梁陣列 汞離子 定量檢測(cè)

【摘要】：研制了一套基于光杠桿原理的微懸臂梁陣列傳感器平臺(tái),并通過使用設(shè)計(jì)制作的微懸臂梁陣列芯片展示其在生物化學(xué)方面的檢測(cè)應(yīng)用。傳感器平臺(tái)使用光導(dǎo)纖維束分別與激光器耦合作為懸臂梁陣列的掃描光源,具有良好的檢測(cè)穩(wěn)定性,檢測(cè)信號(hào)噪聲水平約為2 nm;設(shè)計(jì)制作的微懸臂梁陣列芯片具有良好的平直度,溫度響應(yīng)均勻一致,各梁溫度改變響應(yīng)靈敏度偏差不超過5.0%。將整套傳感系統(tǒng)被用于檢測(cè)水溶液中的Hg2+,檢測(cè)濃度范圍為1~200 ng/m L;同一濃度下微懸臂梁陣列檢測(cè)結(jié)果曲線一致性良好,平均偏差小于15%。在研制儀器平臺(tái)上,分別實(shí)現(xiàn)了自制和國(guó)外商品化芯片對(duì)1.0和0.2 ng/m L樣品的檢測(cè),結(jié)果表明,制作的微懸臂梁陣列芯片的檢測(cè)靈敏度相對(duì)較低,需進(jìn)一步改進(jìn)懸臂梁陣列制作工藝。
[Abstract]:A micro cantilever array sensor platform based on optical lever is developed. By using the designed microcantilever array chip to demonstrate its biochemistry detection application. The sensor platform uses the optical fiber bundle coupled with the laser as the scanning light source of the cantilever beam array. It has good detection stability, the noise level of the detection signal is about 2 nm; The designed microcantilever array chip has good flatness and uniform temperature response. The sensitivity deviation of each beam temperature change response is not more than 5.0. The whole sensing system is used to detect Hg2 in aqueous solution with a concentration range of 1 ~ 200 ng/m / L; The results of microcantilever array detection at the same concentration are consistent with each other, and the average deviation is less than 15. The detection of 1. 0 and 0. 2 ng/m / L samples by commercial chips made by ourselves and abroad has been realized respectively. The results show that the detection sensitivity of the fabricated microcantilever array chips is relatively low. The fabrication process of cantilever beam array should be further improved.
【作者單位】： 中國(guó)科學(xué)院材料力學(xué)行為和設(shè)計(jì)重點(diǎn)實(shí)驗(yàn)室中國(guó)科學(xué)技術(shù)大學(xué)近代力學(xué)系;美奧微系統(tǒng)有限公司;
【基金】：國(guó)家自然科學(xué)基金項(xiàng)目(Nos.11627803,11502265,11472266) 中國(guó)科學(xué)院戰(zhàn)略性先導(dǎo)科技專項(xiàng)(B類)(No.XDB22040502)資助~~
【分類號(hào)】：TP212
【正文快照】： 本文系國(guó)家自然科學(xué)基金項(xiàng)目(Nos.11627803,11502265,11472266)及中國(guó)科學(xué)院戰(zhàn)略性先導(dǎo)科技專項(xiàng)(B類)(No.XDB22040502)資助*E-mail:wushq@ustc.edu.cn;zhangqc@ustc.edu.cn1引言微懸臂梁傳感技術(shù)是目前在生物化學(xué)檢測(cè)領(lǐng)域具有廣泛發(fā)展前景的傳感技術(shù)手段。微懸臂梁傳感器的設(shè)，

本文編號(hào)：1402685