本文選題：擴(kuò)充型動(dòng)態(tài)楔形板　切入點(diǎn)：楔形因子　出處：《南方醫(yī)科大學(xué)學(xué)報(bào)》2015年02期 　論文類型：期刊論文

【摘要】：目的研究瓦里安擴(kuò)充型動(dòng)態(tài)楔形板楔形因子計(jì)算修正方法,比較楔形野中心點(diǎn)處手工和治療計(jì)劃系統(tǒng)計(jì)算結(jié)果相對(duì)測(cè)量結(jié)果的劑量/跳數(shù)差異。方法對(duì)于瓦里安直線加速器的6 MV、10 MV光子線,使用指形電離室測(cè)量水下10 cm處不同動(dòng)態(tài)楔形野的楔形因子及射野中心點(diǎn)的劑量,采用治療計(jì)劃系統(tǒng)計(jì)算相應(yīng)射野的劑量/跳數(shù)。使用加速器輸出分割模型手工計(jì)算射野的楔形因子,并采用常數(shù)因子修正手工計(jì)算結(jié)果。對(duì)手工計(jì)算、治療計(jì)劃系統(tǒng)計(jì)算和測(cè)量結(jié)果進(jìn)行比較,分析三種方法下常規(guī)二維治療計(jì)劃下動(dòng)態(tài)楔形野的楔形因子和射野中心點(diǎn)跳數(shù)的誤差。結(jié)果以測(cè)量結(jié)果為標(biāo)準(zhǔn),校正后,手工計(jì)算的楔形因子誤差明顯減小。其中,6 MV光子線下,60°楔形角下對(duì)稱野最大相對(duì)誤差由4.2%減小到1.3%,非對(duì)稱野最大相對(duì)誤差由-4.7%減小到-1.8%。10 MV所有楔形野相對(duì)誤差由最大-3.0%降低到1.1%。手工計(jì)算跳數(shù)與測(cè)量結(jié)果對(duì)比,對(duì)稱野相應(yīng)射野跳數(shù)計(jì)算相對(duì)誤差在2%以內(nèi),但部分非對(duì)稱野最大相對(duì)誤差超過5%。比較治療計(jì)劃系統(tǒng)計(jì)算結(jié)果與測(cè)量結(jié)果,其最大相對(duì)誤差小于1.5%。結(jié)論使用常數(shù)因子可以有效減小輸出分割模型計(jì)算楔形因子的誤差。對(duì)于常規(guī)二維治療計(jì)劃楔形野的跳數(shù)計(jì)算來說,校正后對(duì)稱野射野中心點(diǎn)的計(jì)算結(jié)果符合臨床治療要求,但對(duì)于射野邊緣與等中心最短距離小于4 cm的非對(duì)稱野來說,需要使用相應(yīng)的非對(duì)稱射野處方劑量計(jì)算方法,或者采用測(cè)量方法或利用治療計(jì)劃系統(tǒng)計(jì)算相應(yīng)的射野跳數(shù)。
[Abstract]:Aim to study a modified method for calculating the wedge factor of Varian expansion type dynamic wedge plate. The difference of dose / hops between manual and therapeutic planning system calculation results relative to the measured results at the center point of wedge field was compared. Methods for the 6 MV 10 MV photon line of Varian linear accelerator, The wedge factor of different dynamic wedge fields and the dose of the center point of the field were measured by using the finger ionization chamber at the depth of 10 cm below the water. The dose / hops of the corresponding field are calculated by the treatment planning system. The wedge factor of the field is calculated manually by using the accelerator output partition model, and the result is corrected by the constant factor. The calculated and measured results of the treatment planning system are compared, and the errors of the wedge factor of the dynamic wedge field and the number of hops at the center of the field under the conventional two dimensional treatment plan are analyzed under the three methods. The error of wedge factor calculated by hand is obviously reduced, in which the maximum relative error of symmetric field at 60 擄wedge angle is reduced from 4.2% to 1.3, and the maximum relative error of asymmetric field is reduced from -4.7% to -1.8 .10 MV relative error of all wedge fields. From the maximum of -3.0% to 1.1. The number of hops calculated by hand is compared with the measured results. The relative error of the calculation of the corresponding field hops of symmetric field is less than 2%, but the maximum relative error of partial asymmetric field is more than 5. The calculated results of the treatment plan system are compared with the measured results. The maximum relative error is less than 1.5. Conclusion using constant factor can effectively reduce the error of calculating wedge factor in output segmentation model. The calculated results of the center point of the symmetrical field after correction accord with the requirement of clinical treatment. However, for the asymmetric field with the shortest distance from the edge of the field to the isocenter less than 4 cm, it is necessary to use the corresponding method to calculate the dose of the asymmetric field prescription. Either the measurement method or the treatment plan system is used to calculate the corresponding field jump.
【作者單位】： 中山大學(xué)腫瘤防治中心//華南腫瘤學(xué)國(guó)家重點(diǎn)實(shí)驗(yàn)室//腫瘤醫(yī)學(xué)協(xié)同創(chuàng)新中心;
【基金】：國(guó)家自然科學(xué)基金(81272486) 廣東省教育部產(chǎn)學(xué)研重點(diǎn)項(xiàng)目(2012B091000144)~~
【分類號(hào)】：TH774

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