【摘要】：目的循證評(píng)價(jià)幽門螺桿菌(H.pylori)感染管理指南質(zhì)量,以促進(jìn)高質(zhì)量指南的臨床應(yīng)用,并推動(dòng)低質(zhì)量指南的持續(xù)改進(jìn)。方法計(jì)算機(jī)檢索PubMed、CNKI和GIN(Guidelines International Network)、NGC(National Guideline Clearinghouse)、NICE(National Institute for Health and Clinical Excellence)、SIGN(Scottish Intercollegiate Guidelines Network)、ASHP(American Society of Health-System Pharmacists)網(wǎng)站及Google搜索引擎,搜集近10年H.pylori感染管理的相關(guān)指南,檢索時(shí)限均為2005年1月至2015年4月。采用AGREEⅡ工具評(píng)價(jià)指南的方法學(xué)質(zhì)量,比較不同指南在H.pylori根除指征及推薦的一線根除療法上的不同。結(jié)果共納入13個(gè)指南。在6個(gè)評(píng)價(jià)領(lǐng)域中,清晰性領(lǐng)域表現(xiàn)最佳,平均得分為92.6%(78%~100%);編撰的獨(dú)立性領(lǐng)域表現(xiàn)最差,平均得分為35.7%(0~92%);范圍與目的、指南制定參與人員、制定嚴(yán)謹(jǐn)性、應(yīng)用性領(lǐng)域表現(xiàn)一般,平均得分分別為70.2%(39%~100%)、41.4%(22%~75%)、41.7%(11%~82%)、58.1%(35%~85%)。結(jié)論 H.pylori感染管理指南總體質(zhì)量不高。有待開(kāi)發(fā)可信賴的、高質(zhì)量的H.pylori感染管理指南,尤其在編撰獨(dú)立性、指南制定參與人員及制定嚴(yán)謹(jǐn)性三個(gè)方面需要進(jìn)一步提高。
[Abstract]:Objective to evaluate the quality of management guidelines for Helicobacter pylori (H.pylori) infection based on evidence, so as to promote the clinical application of high quality guidelines and to promote the continuous improvement of low quality guidelines. Methods PubMed,CNKI and GIN (Guidelines International Network), NGC (National Guideline Clearinghouse), NICE (National Institute for Health and Clinical Excellence), SIGN (Scottish Intercollegiate Guidelines Network), ASHP (American Society of Health-System Pharmacists websites and Google search engine were searched by computer. To collect the relevant guidelines for the management of H.pylori infection in recent 10 years, the search time is from January 2005 to April 2015. The AGREE 鈪，

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