【摘要】：背景 目前,經(jīng)皮椎體后凸成形術(shù)(PKP)和經(jīng)皮椎體成形術(shù)(PVP)技術(shù)已廣泛應(yīng)用于臨床骨質(zhì)疏松性椎體骨折的微創(chuàng)外科治療,對兩種術(shù)式的選擇在臨床上還沒有嚴(yán)格統(tǒng)一的選擇標(biāo)準(zhǔn)。 目的 對國內(nèi)外發(fā)表的經(jīng)皮椎體后凸成形術(shù)與經(jīng)皮椎體成形術(shù)治療骨質(zhì)疏松性椎體骨折的隨機(jī)對照試驗(yàn)、臨床對照試驗(yàn)進(jìn)行系統(tǒng)評價,為臨床應(yīng)用提供一定的證據(jù)并為下一步研究指導(dǎo)方向。 方法 計(jì)算機(jī)檢索1998年1月至2012年1月的The Cochrane Library、PubMed、EMBASE.美國科學(xué)引文索引數(shù)據(jù)庫、中國生物醫(yī)學(xué)文獻(xiàn)數(shù)據(jù)庫、中國學(xué)術(shù)期刊網(wǎng)絡(luò)出版總庫、數(shù)據(jù)化期刊全文數(shù)據(jù)庫和1998年1月至2011年12月的中文科技期刊數(shù)據(jù)庫,手工檢索谷歌、雅虎和百度等綜合搜索引擎,篩選研究收集數(shù)據(jù)后,分析數(shù)據(jù)并進(jìn)行系統(tǒng)評價,解釋結(jié)果并得出結(jié)論。 結(jié)果 共納入5個相關(guān)研究,研究結(jié)果提示,PEP組與PVP組在術(shù)后1月內(nèi)、術(shù)后6月、術(shù)后1年的VAS評分比較,差異無統(tǒng)計(jì)學(xué)意義(P0.05)；兩組分別在腰部疼痛程度和Oswestry評分方面比較,差異無統(tǒng)計(jì)學(xué)意義(P0.05)；兩組術(shù)后椎體高度比較,差異無統(tǒng)計(jì)學(xué)意義(P0.05),但敏感性分析示該結(jié)果可信度不大；兩組術(shù)后1月內(nèi)、術(shù)后6月、術(shù)后1年的椎體高度壓縮率比較,PKP組低于PVP組(P0.05)；兩組術(shù)后1月內(nèi)、術(shù)后6月、術(shù)后1年的后凸角比較,PKP組低于PVP組(P0.05)；兩組分別在手術(shù)時間、骨水泥量及鄰椎骨折方面比較,差異無統(tǒng)計(jì)學(xué)意義(P0.05)：兩組骨水泥滲漏情況比較,PKP組安全性高于PVP組(P0.05)。結(jié)論 PKP對椎體高度的恢復(fù)及椎體后凸畸形的矯正優(yōu)于PVP,并且在在骨水泥滲漏的安全性方面優(yōu)于PVP。
[Abstract]:Background at present, percutaneous kyphoplasty (PKP) and percutaneous vertebroplasty (PVP) have been widely used in minimally invasive surgical treatment of osteoporotic vertebral fractures. There is no strict and uniform criteria for the selection of the two surgical procedures in clinical practice. Objective to evaluate the randomized controlled trials and clinical controlled trials of percutaneous kyphoplasty and percutaneous vertebroplasty for osteoporotic vertebral fractures published at home and abroad. To provide some evidence for clinical application and guide future research. Methods computer retrieval of The Cochrane Library,PubMed,EMBASE. from January 1998 to January 2012 American Science Citation Index Database, Chinese Biomedical Literature Database, Chinese academic Journals Network Publishing Master Database, full text Database of Chinese academic Journals and Chinese Sci-tech Journals Database from January 1998 to December 2011. Yahoo and Baidu and other comprehensive search engines, screening research data collection, data analysis and systematic evaluation, interpretation and conclusions. Results five related studies were included. The results showed that there was no significant difference in VAS scores between PEP group and PVP group within 1 month, 6 months and 1 year after operation (P0.05). There was no significant difference in lumbar pain and Oswestry score between the two groups (P0.05), but there was no significant difference in vertebral height between the two groups (P0.05), but the sensitivity analysis showed that the reliability of the results was not significant. The vertebral height compression ratio in the PKP group was lower than that in the PVP group (P0.05), and the kyphoid angle in the PKP group was lower than that in the PVP group within 1 month, 6 months and 1 year after operation (P0.05). There was no significant difference in operation time, bone cement content and adjacent vertebral fracture between the two groups (P0.05). The safety of PKP group was higher than that of PVP group (P0.05). Conclusion PKP is superior to PVP, in the recovery of vertebral height and correction of kyphosis and is superior to PVP. in the safety of bone cement leakage.
【學(xué)位授予單位】：成都中醫(yī)藥大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2012
【分類號】：R687.3

【參考文獻(xiàn)】

相關(guān)期刊論文 前10條

1 鄧忠良;一次性注射器加壓注吸裝置的設(shè)計(jì)及在椎體成形術(shù)中的應(yīng)用[J];重慶醫(yī)學(xué);2005年04期

2 ;原發(fā)性骨質(zhì)疏松癥診治指南(2011年)[J];中華骨質(zhì)疏松和骨礦鹽疾病雜志;2011年01期

3 李濟(jì)安;;應(yīng)用PVP與PKP治療骨質(zhì)疏松脊柱壓縮性骨折的比較[J];中外醫(yī)療;2011年14期

4 李雪松;聶浩雄;張麗梅;龐尊中;李應(yīng)龍;;經(jīng)皮椎體成形術(shù)和經(jīng)皮椎體后凸成形術(shù)治療骨質(zhì)疏松性椎體壓縮骨折[J];中國介入影像與治療學(xué);2009年01期

5 王開化;;PKP和PVP治療骨質(zhì)疏松性椎體壓縮性骨折效果比較[J];山東醫(yī)藥;2011年35期

6 王靖;沈雄杰;黃象望;;經(jīng)皮椎體成形術(shù)與經(jīng)皮椎體后凸成形術(shù)治療骨質(zhì)疏松性椎體壓縮骨折療效比較[J];現(xiàn)代中西醫(yī)結(jié)合雜志;2011年18期

7 徐寶山,唐天駟,胡永成,倪才方,楊惠林;椎體成形術(shù)對胸腰椎爆裂型骨折的治療意義[J];中華骨科雜志;2002年12期

8 楊惠林,牛國旗,梁道臣,王根林,孟斌,陳亮,陸儉,周云,毛海青,趙劉軍,劉小勇,顧曉暉,倪才方,唐天駟;單球囊與雙球囊后凸成形術(shù)對椎體復(fù)位作用的研究[J];中華外科雜志;2004年21期

9 朱佳俊;屠冠軍;;椎體后凸成形術(shù)與椎體成形術(shù)治療骨質(zhì)疏松性椎體壓縮骨折的Meta分析[J];中國脊柱脊髓雜志;2011年10期

10 申勇;任虎;張英澤;智新力;丁文元;徐佳欣;楊大龍;;經(jīng)皮椎體后凸成形術(shù)治療骨質(zhì)疏松性椎體壓縮骨折骨水泥滲漏的相關(guān)因素分析[J];中國修復(fù)重建外科雜志;2010年01期

，

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