本文關(guān)鍵詞： 納米針狀表面改性 仿生多孔鈦 成骨性能 冷凍鑄造 熱氧化法　出處：《Transactions of Nonferrous Metals Society of China》2017年08期 　論文類型：期刊論文

【摘要】：通過冷凍鑄造和熱氧化法制備一種新型兼具抗菌功能和良好骨整合性能的納米針狀表面改性仿生多孔鈦植入體。分析和表征仿生多孔鈦植入體的孔隙形貌和尺寸、力學(xué)性能和體外成骨性能。結(jié)果表明:當控制冷凍鑄造工藝中漿料中鈦粉體積比為10%時,多孔試樣的孔隙度為(58.32±1.08)%、孔徑為(126.17±18.64)μm、壓縮強度為(58.51±20.38)MPa、彈性模量為(1.70±0.52)GPa。在1200°C燒結(jié)1 h,多孔試樣的孔隙度為(58.24±1.50)%、孔徑為(124.16±13.64)μm、壓縮強度為(54.77±27.55)MPa、彈性模量為(1.63±0.30)GPa。通過熱氧化方法在多孔鈦植入體試樣的孔隙表面制備出均勻分布的納米針狀結(jié)構(gòu)。通過對工藝的優(yōu)化,制備出具有良好孔隙形貌和尺寸,同時具備良好力學(xué)性能和體外成骨性能的納米針狀表面改性仿生多孔鈦植入體,具有重要的臨床應(yīng)用前景。
[Abstract]:A novel nano-needle surface modified biomimetic porous titanium implant was prepared by freezing casting and thermal oxidation. The pore morphology and size of the biomimetic porous titanium implant were analyzed and characterized. Mechanical properties and osteogenic properties in vitro. The results show that when the volume ratio of titanium powder in the slurry is 10, when the volume ratio of titanium powder in the slurry is 10, The porosity of porous specimen was 58.32 鹵1.08m, pore diameter was 126.17 鹵18.64 渭 m, compressive strength was 58.51 鹵20.38mPa, elastic modulus was 1.70 鹵0.52GPa.The porosity of porous specimen was 58.24 鹵1.50 渭 m, pore diameter was 124.16 鹵13.64 渭 m, compressive strength was 54.77 鹵27.55MPa, elastic modulus was 1.63 鹵0.30GPa. by thermal oxidation method, porosity of porous specimen was 58.24 鹵1.50 渭 m, pore diameter was 124.16 鹵13.64 渭 m, compressive strength was 54.77 鹵27.55 MPA, elastic modulus was 1.63 鹵0.30GPa. the porosity of porous specimen was 58.24 鹵1.50 渭 m, pore diameter was 124.16 鹵13.64 渭 m, compressive strength was 54.77 鹵27.55 MPA, elastic modulus was 1.63 鹵0.30GPa. A uniform distribution of nano-needle structure was prepared on the pore surface of the sample. The biomimetic porous titanium implants with good pore morphology and size, good mechanical properties and osteogenic properties in vitro were prepared, which have important clinical application prospects.
【作者單位】： 中南大學(xué)湘雅三醫(yī)院;中南大學(xué)粉末冶金國家重點實驗室;
【基金】：Projects(51290295,51305464) supported by the National Natural Science Foundation of China Project(2016JJ6156) supported by the Natural Science Foundation of Hunan Province,China Project(2016JC2064) supported by the Key Research and Development Program of Hunan Province,China Project(20130162120094) supported by the Specialized Research Fund for the Doctoral Program of Higher Education,China
【分類號】：R318.08;TG292

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