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多縫隙電磁加熱針的研究

發(fā)布時間:2018-08-18 12:47
【摘要】:對于肝臟腫瘤性疾病的治療,一直都是全世界醫(yī)學工作者所關心的問題。微波醫(yī)療這一概念的提出,使得通過微波進行肝臟腫瘤治療的技術成為當今最活躍的研究熱點之一。微波醫(yī)療提出了一種新型的治療腫瘤的方式,啟發(fā)人們將微波學和生物學廣泛結(jié)合。臨床實驗結(jié)果表明,將微波加熱技術用于腫瘤的治療的療效相比于其他放射、化療等方式更為有效。而且,微波加熱技術的設備簡單、操作方便、費用相對低廉,更主要的是,微波加熱治療腫瘤并發(fā)癥少,副作用小,顯著地提高了病患的生存質(zhì)量。微波加熱針是微波加熱在腫瘤治療中最為關鍵的器件,也是目前微波加熱在腫瘤治療當中的研究重點之一。本文在調(diào)研國內(nèi)外相關文獻的基礎上,針對多縫隙電磁加熱針進行研究和設計,爭取在微波加熱針的加熱長度和加熱形狀上有所創(chuàng)新,主要研究工作和創(chuàng)新內(nèi)容如下:一、首先對傳統(tǒng)的微波加熱針進行理論分析研究,并通過HFSS和COMSOL等相關仿真軟件進行建模仿真設計出一種工作于2.45 GHz的單極子微波加熱針,并設計加工完成實驗。二、為了保護實驗人員在進行體外大功率活體豬肝實驗時不受電磁輻射的傷害,本文利用仿真軟件HFSS設計分析并加工一種透明可視化的吸波暗室,用于本論文中設計出的所有的微波加熱針的體外活體豬肝實驗。在有效保障實驗人員不被大功率微波輻射的同時,還能讓實驗人員更好的觀察和記錄消融加熱效果實時變化效果。三、在單極子電磁加熱針的基礎上,利用HFSS和ADS聯(lián)合仿真,提取了縫隙的等效電路模型,運用MATLAB軟件擬合出了縫隙等效電路結(jié)構(gòu)的各個參數(shù)與縫隙寬度的數(shù)學關系式,并利用這種方法初步設計了多種縫隙加熱針,并在HFSS中進行了驗證,簡化并方便了后續(xù)的仿真設計。提出了添加金屬套筒結(jié)構(gòu)這一方式,改變了加熱形狀,實現(xiàn)了“一針多用”的效果。四、最后在多縫隙電磁加熱針的基礎上,設計加工并實驗多根電磁加熱針同時工作的情形,擴大了電磁加熱針的加熱范圍,并聯(lián)系華西醫(yī)院的科研人員,進行了動物活體實驗,并記錄了實驗數(shù)據(jù)。
[Abstract]:The treatment of liver neoplastic diseases has always been concerned by medical workers all over the world. With the development of the concept of microwave therapy, microwave therapy for liver tumors has become one of the most active research topics. Microwave therapy has proposed a new way to treat cancer and inspired the wide combination of microwave and biology. The clinical results show that microwave heating is more effective than other methods such as radiotherapy and chemotherapy. Moreover, microwave heating technology has the advantages of simple equipment, convenient operation and relatively low cost. More importantly, microwave heating therapy has fewer complications and less side effects, which significantly improves the quality of life of patients. Microwave heating needle is the most important device of microwave heating in tumor treatment, and it is also one of the key points of microwave heating in tumor therapy. Based on the domestic and foreign literature, this paper studies and designs the multi-slot electromagnetic heating needle, and tries to innovate the heating length and shape of the microwave heating needle. The main research and innovation contents are as follows: 1. Firstly, the traditional microwave heating needle is studied theoretically, and a monopole microwave heating needle working in 2.45 GHz is designed by HFSS and COMSOL simulation software, and the experiment is completed. Secondly, in order to protect the experimenter from electromagnetic radiation in the experiment of high power pig liver in vitro, a transparent visual absorbing chamber was designed and processed by using the simulation software HFSS. In this paper, designed for all microwave heating needle in vitro porcine liver experiment. It can not only protect the experimenter from high power microwave radiation, but also enable the experimenter to observe and record the real time effect of ablation heating. Thirdly, on the basis of monopole electromagnetic heating needle, the equivalent circuit model of slot is extracted by using HFSS and ADS simulation, and the mathematical relationship between the parameters of gap equivalent circuit structure and slot width is fitted by MATLAB software. By using this method, a variety of slot heating needles are preliminarily designed and verified in HFSS, which simplifies and facilitates the subsequent simulation design. The method of adding metal sleeve structure is put forward, and the heating shape is changed, and the effect of "one pin multi-purpose" is realized. Finally, on the basis of the multi-slot electromagnetic heating needle, we designed and processed and experimented with multiple electromagnetic heating needles working at the same time, expanded the heating range of the electromagnetic heating needles, and contacted the researchers in Huaxi Hospital to conduct animal experiments in vivo. The experimental data were recorded.
【學位授予單位】:電子科技大學
【學位級別】:碩士
【學位授予年份】:2017
【分類號】:R735.7;TN015

【參考文獻】

相關期刊論文 前3條

1 趙偉;韋高;陳柏嘉;;近場聚焦微帶陣列天線研究[J];微波學報;2014年02期

2 ;Current treatment for liver metastases from colorectal cancer[J];World Journal of Gastroenterology;2003年02期

3 黃玉璽,萬柏坤,張力新,楊春梅,劉慶凱;水冷式雙縫微波偶極子熱場分布特征的仿真研究[J];北京生物醫(yī)學工程;2001年01期

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