脈沖Ho:YAG激光誘導(dǎo)水介質(zhì)空化效應(yīng)及其對骨硬組織消融的影響
[Abstract]:Reducing thermal injury and improving ablation efficiency are the hot, important and difficult points in laser hard tissue ablation. Current studies have shown that external water intervention can enhance the ablation effect of laser hard tissue, laser induced cavitation effect plays an important role in liquid-mediated ablation, but the relevant mechanism has not been properly explained. Based on the development of laser ablation technology at home and abroad and the requirement of clinical application, this paper takes the pulsed Ho: YAG laser with wavelength of 2.08 渭 m as the radiation source, based on the high speed camera technology. The effect of different water depth and different concentration of ink solution on the pulsation of cavitation and its effect on the ablation of bovine femur was studied. Firstly, the composition, basic components and related characteristics of bone tissue are introduced. The mechanism of direct laser ablation and liquid-mediated ablation of hard tissue is summarized, and the generation, pulsation and collapse of laser cavitation are described. And the influencing factors of cavitation pulsation. Secondly, a high resolution high speed camera is used to photograph the high speed process of the spatiotemporal bubble effect of a pulsed Ho: YAG laser interacting with a water medium. The relationship between the period of cavitation, the maximum transverse width, the maximum longitudinal length and the maximum volume of the cavitation with the depth of the fiber is obtained under different laser energy. Thirdly, the pulsation process of spatiotemporal bubbles of pulse Ho: YAG laser interacting with different concentration of ink solution was monitored by high resolution and high speed camera. The period of cavitation, the maximum transverse width, the maximum longitudinal length and the maximum volume of cavitation increase with the increase of pulse energy, while the absorption coefficient of pure water decreases with the addition of different ink volumes in pure water. Finally, the ablation experiment of bovine femur in different depth of pure water medium and different absorption coefficient of ink solution in air, pure water medium and different absorption coefficient was carried out by using a pulsed Ho: YAG laser at a wavelength of 2.08 渭 m. The changes of surface ablation morphology of bovine femoral bone were evaluated by high speed camera real time Oct scanning system and stereoscopic microscope system. By optimizing the water depth of fiber, liquid medium and laser parameters, the ablation effect without heat damage can be obtained, and the ablation incision depth, smooth edge, regular shape, and higher ablation rate and efficiency can also be obtained.
【學(xué)位授予單位】:福建師范大學(xué)
【學(xué)位級別】:碩士
【學(xué)位授予年份】:2015
【分類號】:Q682;TN249
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