本文選題：微藻DHA油 + 納米乳�。� 參考：《海洋科學(xué)》2017年04期

【摘要】：采用超聲波法制備微藻DHA油納米乳,研究了微藻DHA油納米乳真空冷凍干燥工藝,并對其粉末進(jìn)行了表征。研究結(jié)果表明,當(dāng)凍干曲線為:預(yù)凍: 40℃維持2 h,真空度為0.2 mbar;升華干燥: 30℃維持12 h,真空度為0.2 mbar, 20℃維持2.5 h,真空度為0.15 mbar;解析干燥:25℃維持3 h,真空度為0.15 mbar,且油相與凍干保護(hù)劑的質(zhì)量比為1:4,凍干保護(hù)劑選擇葡萄糖:甘露醇質(zhì)量比為1:3時,制備的納米乳粉末顆粒外觀呈乳白色、均勻細(xì)膩,復(fù)溶速度在10s內(nèi),凍干前粒徑為(175.6±22.1)nm,多分散系數(shù)(PDI)為(0.15±0.62),凍干后粒徑為(211.1±23.5)nm,PDI為(0.152±0.116),差異不大,依舊在納米范圍內(nèi),不僅保證了DHA的長期穩(wěn)定性,還擴(kuò)大了DHA的應(yīng)用范圍,有望成為DHA的新型納米載藥系統(tǒng)。
[Abstract]:Microalgae DHA oil nano-emulsion was prepared by ultrasonic method. The vacuum freeze-drying process of microalgae DHA oil nano-emulsion was studied and its powder was characterized. The results show that When the freeze-drying curve is as follows: prefreezing at 40 鈩，

本文編號：1979055