本文選題：減控體重 + 減重營養(yǎng)食品�。� 參考：《廣州體育學(xué)院學(xué)報》2017年05期

【摘要】：目的:根據(jù)對運動員減控體重的要求和特點,選擇設(shè)計荷葉黃酮配方,并進行本營養(yǎng)品的減重降脂作用及安全性實驗研究。方法:采用體外酶抑制法測定荷葉黃酮對脂肪酶活性的影響;采用營養(yǎng)性肥胖大鼠模型試驗進行荷葉黃酮的減重和降血脂作用研究。MTT法檢測不同濃度荷葉黃酮對3T3-L1前脂肪細胞增殖的影響。油紅染色法定量檢測荷葉黃酮對3T3-L1前脂肪細胞分化的影響。結(jié)果:荷葉黃酮對脂肪酶活性有抑制作用,且隨著濃度的增大而增強。肥胖大鼠模型試驗結(jié)果表明,荷葉黃酮能顯著降低動物的體重,體脂比,血清甘油三酯(TG),膽固醇(TC)、低密度脂蛋白膽固醇(LDL-C)以及HMG-Co A還原酶活性。MTT法檢測結(jié)果顯示,荷葉黃酮可抑制3T3-L1前脂肪細胞的分化,其抑制作用具有濃度依賴性。結(jié)論:補充荷葉黃酮配方營養(yǎng)品具有明顯的減重作用,其作用機制與降低血脂、抑制脂肪細胞分化有關(guān)。
[Abstract]:Objective: according to the requirements and characteristics of weight reduction and control for athletes, the formula of lotus leaf flavonoids was selected and the effects and safety of the nutrient on reducing body weight and lipid were studied. Methods: the effect of flavone on lipase activity in lotus leaves was determined by enzyme inhibition method in vitro. The effects of flavonoids from lotus leaves on the proliferation of preadipocytes before 3T3-L1 were studied by MTT assay. The effects of flavonoids from lotus leaves on the differentiation of preadipocytes from 3T3-L1 were detected quantitatively by oil red staining. Results: flavonoids of lotus leaf inhibited lipase activity and increased with the increase of concentration. The results of obese rat model showed that flavonoids from lotus leaves could significantly reduce the body weight, body fat ratio, serum triglyceride, cholesterol triglyceride, low density lipoprotein cholesterol (LDL-C) and HMG-Co A reductase activity. Lotus leaf flavonoids could inhibit the differentiation of 3T3-L1 preadipocytes in a concentration dependent manner. Conclusion: supplementation of flavonoids from lotus leaves has obvious weight loss effect, and its mechanism is related to lowering blood lipid and inhibiting adipocyte differentiation.
【作者單位】： 惠州學(xué)院體育學(xué)院;
【分類號】：G804.2

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1 樓曉娟;黃勇;鄭樊慧;;荷葉黃酮對小鼠抗疲勞作用的實驗研究[A];第九屆全國體育科學(xué)大會論文摘要匯編(4)[C];2011年

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