本文選題：抗生素 + 多相界面　； 參考：《中國環(huán)境科學(xué)》2017年06期

【摘要】：以CDC生物膜反應(yīng)器模擬給水管網(wǎng)輸配系統(tǒng),探究管網(wǎng)水相、生物膜相和顆粒物相三相界面下6種典型抗生素抗性細(xì)菌的分布特征.反應(yīng)器穩(wěn)定運(yùn)行30d后,出水余氯從0.66mg/L下降到0.26mg/L,出水濁度和顆粒物濃度分別從進(jìn)水的0.08NTU和377counts/mL增高至0.86NTU和4151counts/mL,出水水質(zhì)變差.進(jìn)水中僅有紅霉素和氨芐西林的抗性細(xì)菌的數(shù)量較高,分別為36和99CFU/100mL,出水中,鏈霉素和氨芐西林的抗性細(xì)菌數(shù)量最高,分別為432和155CFU/100mL,遠(yuǎn)遠(yuǎn)高于進(jìn)水中抗性細(xì)菌數(shù)量.生物膜相中異養(yǎng)菌總數(shù)和細(xì)胞總數(shù)達(dá)到了4089CFU/cm~2和1.5×10~6cells/cm~2,鏈霉素和紅霉素的抗性細(xì)菌數(shù)量較高,為3432和2508CFU/cm~2,其抗性細(xì)菌比例分別達(dá)到了83.9%和61.4%.顆粒物相中,氯霉素和氨芐西林的抗性細(xì)菌比例較高,都在45%左右.生物膜和顆粒物都會(huì)給細(xì)菌提供一個(gè)安全穩(wěn)定的生長場所,使細(xì)菌能夠抵抗殘留消毒劑和部分抗生素的抑制作用,更易產(chǎn)生耐藥性,對人體健康的威脅也更大.
[Abstract]:The distribution system of water supply pipe network was simulated with CDC biofilm reactor, and the distribution characteristics of 6 typical antibiotic resistant bacteria in water phase, biofilm phase and particle phase interface were investigated. After the reactor operated steadily for 30d, the effluent chlorine was reduced from 0.66mg/L to 0.26mg/L, and the turbidity and particle concentration of the effluent were from the 0.08NTU and 377counts of the influent respectively. The water quality of /mL increased to 0.86NTU and 4151counts/mL. The number of resistant bacteria of only erythromycin and ampicillin was 36 and 99CFU/100mL, and the number of resistant bacteria in the water, streptomycin and ampicillin was the highest, 432 and 155CFU/100mL respectively, which was much higher than the number of resistant bacteria in the influent. The total number of bacteria and the total number of cells reached 4089CFU/cm~2 and 1.5 x 10~6cells/cm~2. The number of resistant bacteria of streptomycin and erythromycin was higher, 3432 and 2508CFU/cm~2, and the proportion of resistant bacteria reached 83.9% and 61.4%. particles respectively. The proportion of chloramphenicol and ampicillin resistant fine bacteria was higher, both around 45%. Biofilm and particulate matter. Bacteria can provide a safe and stable growth place for bacteria to resist the inhibitory effects of residual disinfectants and some antibiotics, more susceptible to resistance, and more threat to human health.

【作者單位】： 北京工商大學(xué)環(huán)境科學(xué)與工程系;軍事醫(yī)學(xué)科學(xué)院疾病預(yù)防控制所;
【基金】：國家自然科學(xué)基金資助項(xiàng)目(51408010,51608011) 北京工商大學(xué)兩科基金培育項(xiàng)目(LKJJ2016-17)
【分類號】：TU991.25
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本文編號：1824204