【摘要】：干細胞是一類具有自我更新能力的多潛能細胞,在一定的條件下,可分化為多種功能細胞。而干細胞因子是指可靶向調控干細胞的干性維持、定向分化等特性的重要因子,以及在干細胞治療中產生的、對其修復損傷具有關鍵作用的活性因子。近年來,干細胞逐漸被應用到各種人類疾病的治療中,但其臨床應用仍然受到多種因素的制約。干細胞因子治療為解決及避免這些問題帶來了曙光,有望成為未來干細胞治療的新方向。
[Abstract]:Stem cells are multi-potential cells with self-renewal ability. Under certain conditions, stem cells can be differentiated into multi-functional cells. Stem cell factor (SCF) is an important factor that can be targeted to regulate stem cell dryness maintenance, directional differentiation and other characteristics, as well as the active factor which is produced in stem cell therapy and plays a key role in the repair of stem cell injury. In recent years, stem cells have been gradually used in the treatment of various human diseases, but their clinical application is still restricted by many factors. Stem cell factor therapy brings the dawn to solve and avoid these problems, and it is expected to be a new direction of stem cell therapy in the future.
【作者單位】： 中國科學院上海生命科學研究院健康科學研究所;上海交通大學附屬第一人民醫(yī)院;上海交通大學醫(yī)學院基礎醫(yī)學院;
【基金】：中國科學院戰(zhàn)略性先導科技專項(XDA01040200) 國家自然科學基金重點項目(NSF81130057);國家自然科學基金面上項目(NSF81373164) 國家科技部973重大科學研究計劃(2011CB966200)
【分類號】：R45

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