北京社區(qū)人群血漿葉酸水平及其影響因素的相關性研究
[Abstract]:Objective to investigate the plasma folic acid level and its related factors in Beijing community. Methods A cross-sectional study was conducted to investigate the level of plasma folic acid in Shijingshan community residents in Beijing. A total of 5,227 subjects were included in the study. Results the median of plasma folic acid (P25 / P75) was 6.18 (4.98 ~ 8.18) ng / ml in the study group, and 5.29 (4.49 ~ 6.75) ng / ml in male, which was significantly lower than that in female [6.79 (5.45 ~ 9.02) ng/ml]. The multivariate linear regression analysis of plasma folic acid level (natural logarithm) showed that the individual folic acid level (natural logarithm) was lower in obesity (尾 -0.037) and smoking (尾 -0.118 P0.000 1). At a higher age (尾 = 0.003), female (尾 = 0.186), higher educational level (尾 = 0.039), exercise for not less than 5 days a week (尾 = 0.037) and vitamin B supplementation (尾 = 0.299P ~ (0.000 1), plasma folic acid level (natural logarithm) was higher than that of group B vitamin supplement (尾 -0.299p _ (0.0001) for at least 3 days per week in the last three months. By sex stratification analysis, obesity and exercise were only associated with folic acid level (natural logarithm) of women (P0.05), while other factors had no gender difference on the trend of folic acid. Conclusion the level of plasma folic acid in Beijing community population is low, and individual differences, lifestyle and vitamin supplementation influence the level of folic acid.
【作者單位】: 北京大學第一醫(yī)院心血管內科;
【基金】:密歇根大學-北京大學醫(yī)學部轉化醫(yī)學聯(lián)合研究項目(BMU20110177)
【分類號】:R446.1
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