【摘要】：目的:探討靜脈注射釓對(duì)比劑的全身性不良反應(yīng)發(fā)生情況。方法:利用對(duì)比劑安全信息系統(tǒng)的數(shù)據(jù),搜集行MR增強(qiáng)檢查的18540例連續(xù)患者的病例資料,對(duì)注射釓對(duì)比劑后的全身性反應(yīng)進(jìn)行統(tǒng)計(jì),分析不良事件出現(xiàn)時(shí)間及其與對(duì)比劑的相關(guān)性,分為急性不良反應(yīng)(1h)、遲發(fā)性不良反應(yīng)(1h~1w)和晚遲發(fā)不良反應(yīng)(1w)三類,進(jìn)一步將不良反應(yīng)分為輕、中、重度三類,分別進(jìn)行統(tǒng)計(jì)分析。結(jié)果:18540例共發(fā)生全身性不良反應(yīng)24例,總發(fā)生率為0.13%。急性不良反應(yīng)16例(0.09%),其中輕度9例、中度4例、重度3例。遲發(fā)性不良反應(yīng)8例(0.04%),其中輕度6例、中度2例。無(wú)晚遲發(fā)不良反應(yīng)。結(jié)論:MR增強(qiáng)檢查注射釓對(duì)比劑發(fā)生全身性不良反應(yīng)的概率很低,但有發(fā)生急性重度不良反應(yīng)的可能,應(yīng)予以關(guān)注。
[Abstract]:Objective: to investigate the occurrence of systemic adverse reactions of intravenous gadolinium contrast agent. Methods: using the data of contrast agent safety information system, the data of 18540 consecutive patients with Mr enhancement were collected, and the systemic response after gadolinium contrast injection was statistically analyzed. The occurrence time of adverse events and their correlation with contrast agents were analyzed and divided into three categories: acute adverse reactions (1h), delayed adverse reactions (1h~1w) and late delayed adverse reactions (1w). The adverse reactions were further divided into three categories: mild, moderate and severe. Statistical analysis was carried out respectively. Results there were 24 cases of systemic adverse reactions in 18540 cases, the total incidence was 0.13%. There were 16 cases (0.09%) of acute adverse reactions, including mild 9 cases, moderate 4 cases, severe 3 cases. Delayed adverse reactions were found in 8 cases (0.04%), including mild 6 cases and moderate 2 cases. There were no late adverse reactions. Conclusion the probability of systemic adverse reactions in contrast-gadolinium injection is very low, but the possibility of acute and severe adverse reactions should be paid attention to.
【作者單位】： 北京大學(xué)第一醫(yī)院醫(yī)學(xué)影像科;
【分類號(hào)】：R445.2

【相似文獻(xiàn)】

相關(guān)期刊論文 前10條

1 R.J.McDonald;J.S.McDonald;J.P.Bida;R.E.Carter;C.J.Fleming;S.Misra;鐘W氂，

本文編號(hào)：2131727