本文選題：持續(xù)性軀體形式疼痛障礙 + 局部一致性��； 參考：《重慶醫(yī)學(xué)》2016年31期

【摘要】：目的采用靜息態(tài)功能磁共振局部一致性(ReHo)技術(shù),觀察持續(xù)性軀體形式疼痛障礙(PSPD)患者腦局部ReHo值。方法納入21例以頭痛為主要癥狀的PSPD患者和17例年齡、性別相匹配的健康對(duì)照者,所有被試者行靜息態(tài)功能磁共振,對(duì)磁共振數(shù)據(jù)進(jìn)行分析得到ReHo結(jié)果,然后對(duì)比PSPD患者組與健康對(duì)照組的差異。結(jié)果與健康對(duì)照組比較,PSPD患者雙側(cè)額葉ReHo值升高,而雙側(cè)枕葉、雙側(cè)直回、右側(cè)小腦后葉、右側(cè)中央旁小葉、左側(cè)顳中回ReHo值降低(P0.01)。結(jié)論P(yáng)SPD患者相關(guān)腦區(qū)神經(jīng)元活動(dòng)一致性存在改變,這種改變可能是導(dǎo)致PSPD患者發(fā)病的相關(guān)因素之一。
[Abstract]:Objective to observe the regional ReHo of patients with persistent somatoform pain disorder (SPD) by resting functional magnetic resonance imaging (MRI). Methods Twenty-one patients with PSPD with headache as the main symptom and 17 healthy controls with age and sex matched underwent resting functional magnetic resonance imaging (fMRI). The results of ReHo were analyzed. Then the difference between PSPD group and healthy control group was compared. Results compared with the control group, the ReHo value of bilateral frontal lobe in patients with PSPD increased, while the ReHo value of bilateral occipital lobe, bilateral straight gyrus, right posterior cerebellar lobe, right paracentral lobe and left middle temporal gyrus decreased P0.01. Conclusion there is a change in neuronal activity consistency in PSPD patients, which may be one of the related factors leading to the pathogenesis of PSPD.
【作者單位】： 第三軍醫(yī)大學(xué)西南醫(yī)院神經(jīng)內(nèi)科;第三軍醫(yī)大學(xué)西南醫(yī)院放射科;第三軍醫(yī)大學(xué)護(hù)理學(xué)院心理教研室;
【分類號(hào)】：R402
，

本文編號(hào)：1898053