本文選題：老年 + 感染性休克�。� 參考：《實(shí)用醫(yī)學(xué)雜志》2016年22期

【摘要】：目的:探討小劑量普通肝素對(duì)老年感染性休克患者血清降鈣素原及肝素結(jié)合蛋白表達(dá)的影響及臨床意義。方法:選取感染性休克患者80例,隨機(jī)分為對(duì)照組和小劑量普通肝素治療組,每組各40例患者,對(duì)照組給予常規(guī)抗休克治療,小劑量普通肝素治療組在常規(guī)抗休克治療的基礎(chǔ)上給予患者小劑量普通肝素治療,治療1周內(nèi)動(dòng)態(tài)檢測(cè)兩組患者血清降鈣素原與肝素結(jié)合蛋白變化及進(jìn)行APACHEⅡ評(píng)分。結(jié)果:對(duì)照組治療后第1、3天血清降鈣素原、肝素結(jié)合蛋白及APACHEⅡ評(píng)分逐漸升高(P0.05),于治療后第5天逐漸下降,治療后第7天血清降鈣素原、肝素結(jié)合蛋白及APACHEⅡ評(píng)分低于治療前水平(P㧐0.05)。與對(duì)照組比較,小劑量普通肝素治療組治療前及治療后第1天血清降鈣素原、肝素結(jié)合蛋白及APACHEⅡ評(píng)分無明顯變化,差異無統(tǒng)計(jì)學(xué)意義(P㧐0.05),小劑量普通肝素治療組于治療后第3、5、7天血清降鈣素原、肝素結(jié)合蛋白及APACHEⅡ評(píng)分均低于對(duì)照組(P0.05),同時(shí)小劑量普通肝素治療組治療后第3、5、7天血清降鈣素原、肝素結(jié)合蛋白及APACHEⅡ評(píng)分均低于治療前水平(P0.05)。結(jié)論:小劑量普通肝素能有效降低老年感染性休克患者血清降鈣素原及肝素結(jié)合蛋白的表達(dá)水平,在老年感染性休克的治療中具有臨床價(jià)值。
[Abstract]:Objective: to investigate the effect and clinical significance of low dose heparin on serum procalcitonin and heparin binding protein expression in elderly patients with septic shock. Methods: 80 patients with septic shock were randomly divided into control group and small dose heparin treatment group with 40 patients in each group. The control group was treated with routine antishock therapy. The low dose heparin group was treated with low dose common heparin on the basis of routine antishock therapy. The changes of serum procalcitonin and heparin binding protein and APACHE 鈪，

本文編號(hào)：1893449