本文選題：經(jīng)顱磁刺激 + 腦電信號(hào)��； 參考：《燕山大學(xué)》2015年碩士論文

【摘要】：經(jīng)顱磁刺激(Transcranial Magnetic Stimulation,TMS),是一種無(wú)痛、無(wú)創(chuàng)的綠色治療方法,磁場(chǎng)可以無(wú)衰減地經(jīng)過(guò)顱骨直接作用到大腦神經(jīng)。在實(shí)際應(yīng)用中,并不局限于對(duì)大腦組織的刺激,外周的神經(jīng)肌肉也同樣有效。目前,經(jīng)顱磁刺激技術(shù)得到了廣泛使用,通過(guò)改變磁刺激信號(hào)的刺激頻率可以達(dá)到興奮或抑制局部大腦皮質(zhì)功能的目的�，F(xiàn)有對(duì)TMS技術(shù)的使用發(fā)現(xiàn)其對(duì)腦電信號(hào)有顯著的影響效果,但是需要一種在TMS環(huán)境下的腦電采集設(shè)備,來(lái)進(jìn)一步了解TMS技術(shù)對(duì)于腦電采集及分析的影響。論文設(shè)計(jì)了一種基于FPGA(Field-Programmable Gate Array,現(xiàn)場(chǎng)可編程門陣列)的TMS刺激環(huán)境下的生物電信號(hào)采集設(shè)備。TMS刺激環(huán)境下,會(huì)在皮膚表層誘發(fā)一個(gè)很強(qiáng)的電場(chǎng),可以使放大器在很長(zhǎng)的持續(xù)時(shí)間內(nèi)處于飽和狀態(tài),同時(shí)電源噪聲也會(huì)被TMS刺激器引入信號(hào)采集設(shè)備中。針對(duì)上述噪聲和放大器飽和問(wèn)題,引入全帶寬放大器的概念,對(duì)常規(guī)的生物電信號(hào)采集設(shè)備進(jìn)行了改進(jìn),改進(jìn)了常規(guī)采集設(shè)備的模擬電路,對(duì)引入信號(hào)采集設(shè)備中的直流分量進(jìn)行衰減而不是濾波處理,使其能夠采集到有效的低頻及直流信號(hào);并且將TMS刺激和腦電信號(hào)采集頻率進(jìn)行匹配,在TMS刺激后的作用有效時(shí)間內(nèi)進(jìn)行腦電信號(hào)采集,使得TMS刺激對(duì)采集的影響最小。論文介紹了包括前端放大器的設(shè)計(jì)、模擬/數(shù)字轉(zhuǎn)換電路、數(shù)字處理部分、數(shù)據(jù)傳輸及上位機(jī)接收顯示的完整硬件實(shí)現(xiàn)。此外,介紹了FPGA平臺(tái)上的程序設(shè)計(jì)和核心的算法實(shí)現(xiàn)。包括數(shù)據(jù)采集、USB通信的基本原理和實(shí)現(xiàn)、相關(guān)濾波算法的實(shí)現(xiàn)等。同時(shí)討論了程序設(shè)計(jì)和算法優(yōu)化中的一些關(guān)鍵問(wèn)題。
[Abstract]:Transcranial Magnetic stimulation is a painless and non-invasive green treatment method. Magnetic field can directly affect the brain nerve through the skull without attenuation. In practice, it is not limited to stimulation of brain tissue, peripheral neuromuscular is also effective. At present, transcranial magnetic stimulation (TMS) technology has been widely used. By changing the frequency of magnetic stimulation signals, we can achieve the purpose of stimulating or inhibiting the function of local cerebral cortex. The current use of TMS technology has found that it has a significant effect on EEG signals, but it needs a EEG acquisition equipment under the TMS environment to further understand the impact of TMS technology on EEG acquisition and analysis. In this paper, we design a bioelectric signal acquisition device based on FPGA(Field-Programmable Gate array (field programmable gate array) under TMS stimulation environment, which can induce a strong electric field in the skin surface. The amplifier can be saturated for a long time and the power noise will be introduced into the signal acquisition equipment by the TMS stimulator. Aiming at the above problems of noise and amplifier saturation, the concept of full bandwidth amplifier is introduced, and the conventional bioelectric signal acquisition equipment is improved, and the analog circuit of conventional acquisition equipment is improved. The DC component introduced in the signal acquisition device is attenuated rather than filtered so that it can collect effective low frequency and DC signals, and the frequency of TMS stimulation and EEG signal acquisition is matched. EEG signals were collected within the effective time after TMS stimulation, which made TMS stimulation have the least effect on acquisition. This paper introduces the design of the front-end amplifier, the analog / digital conversion circuit, the digital processing part, the complete hardware realization of the data transmission and the host computer receiving and displaying. In addition, the program design and core algorithm implementation on FPGA platform are introduced. It includes the basic principle and realization of USB communication of data acquisition device, the realization of relevant filtering algorithm and so on. At the same time, some key problems in programming and algorithm optimization are discussed.
【學(xué)位授予單位】：燕山大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2015
【分類號(hào)】：R454;TN911.7

【參考文獻(xiàn)】

相關(guān)期刊論文 前2條

1 董秀潔;楊艷;周游;;FPGA/CPLD選型與設(shè)計(jì)優(yōu)化[J];化工自動(dòng)化及儀表;2009年03期

2 呂浩;唐勁天;;經(jīng)顱磁刺激技術(shù)的研究和進(jìn)展[J];中國(guó)醫(yī)療器械信息;2006年05期

，

本文編號(hào)：1838409