本文選題：導(dǎo)管消融術(shù)　切入點：豬肝　出處：《中國介入影像與治療學(xué)》2016年02期

【摘要】：目的探討不同功率膽道內(nèi)射頻消融后離體豬肝局部膽汁溫度變化及膽道損傷情況。方法選取10個新鮮離體豬肝(膽囊及膽總管中上段完整保留),于DSA下將收集的人膽汁注入豬膽道系統(tǒng),并注入少量對比劑,然后將HabibTMEndoHPB射頻消融導(dǎo)管經(jīng)膽總管引入肝門區(qū)膽管內(nèi)并用縫線將膽總管與消融導(dǎo)管綁緊。10個豬肝消融參數(shù)分別為5 W(120s)、6 W(120s)、7 W(120s)、8 W(120s)、9 W(120s)、10 W(120s)、11 W(120s)、12 W(120s)、13 W(120s)、14 W(120s)。透視下分別于遠端消融電極、距遠端消融電極1、2cm處插入測溫針進行測溫。消融后取消融區(qū)膽管及毗鄰組織送病理檢查評價損傷程度。結(jié)果 10個人膽汁充盈離體豬肝膽道系統(tǒng)消融模型均成功建立,且成功導(dǎo)入射頻消融導(dǎo)管進行消融。測溫顯示消融區(qū)溫度隨功率增加而升高、最高達90.3℃;距遠端消融電極1、2cm處溫度上升不明顯,為28.4~40.2℃。病理檢查顯示消融區(qū)膽管出現(xiàn)全層凝固性壞死,距消融區(qū)1、2cm處膽管及毗鄰肝組織無明顯損傷。結(jié)論膽道內(nèi)消融可使鄰近膽道內(nèi)膽汁溫度有所升高,但對毗鄰非消融區(qū)膽管內(nèi)皮無明顯損傷,提示膽汁熱傳導(dǎo)作用對毗鄰非消融區(qū)膽管及肝組織影響較小。
[Abstract]:Objective to investigate the changes of local bile temperature and bile duct injury in isolated porcine liver after radiofrequency catheter ablation at different power levels. Methods Ten fresh isolated porcine liver (gallbladder and upper common bile duct) were collected under DSA. Human bile is injected into the pig biliary system, And injected a small amount of contrast agent, Then the HabibTMEndoHPB radiofrequency catheter was introduced into the bile duct of the hilar area of the liver and the suture was used to bind the common bile duct and the ablation catheter. The ablation parameters of 10 pig liver were 5 W / 120 s1 / 6 W ~ (12) W ~ (12) W ~ (12) W ~ (12) W ~ (12) W ~ (12) S ~ + ~ (12) W ~ (120) S ~ + ~ 14 W ~ (120) s ~ (-1). The ablation parameters of the liver in 10 pigs were as follows:. After ablation, the bile duct and adjacent tissues in the ablation area were taken to send pathological examination to evaluate the degree of injury. Results the ablation model of isolated porcine hepatobiliary duct system was established successfully in 10 individuals. The temperature measurement showed that the temperature of the ablation area increased with the increase of power, up to 90.3 鈩，

本文編號：1695849