口咽訓(xùn)練治療阻塞型睡眠呼吸暫停綜合征的Meta分析
發(fā)布時(shí)間:2018-03-30 11:53
本文選題:睡眠呼吸暫停綜合征 切入點(diǎn):語音訓(xùn)練 出處:《重慶醫(yī)學(xué)》2016年26期
【摘要】:目的采用Meta分析綜合評(píng)價(jià)口咽訓(xùn)練對(duì)阻塞型睡眠呼吸暫停綜合征(OSAS)的作用。方法利用計(jì)算機(jī)檢索國內(nèi)外發(fā)表的有關(guān)口咽訓(xùn)練治療OSAS的文獻(xiàn),按納入和排除標(biāo)準(zhǔn),經(jīng)質(zhì)量評(píng)價(jià)后確定最終文獻(xiàn),提取有關(guān)指標(biāo)數(shù)據(jù),應(yīng)用RevMan 5.3軟件進(jìn)行分析。結(jié)果共納入6項(xiàng)報(bào)道了多導(dǎo)睡眠圖和嗜睡情況的研究,包括92例研究對(duì)象。Meta分析結(jié)果顯示,口咽訓(xùn)練后患者的呼吸暫停低通氣指數(shù)(AHI)明顯低于訓(xùn)練前,合并后均數(shù)差(MD)=14.26,95%CI(7.54,20.98),Z=4.16(P0.01)。夜間最低血氧飽和度(SaO2)在訓(xùn)練后有顯著提高,合并后MD=-3.66,95%CI(-6.06,-1.26),Z=2.99(P0.01)。Epworth嗜睡量表評(píng)分結(jié)果顯示,口咽訓(xùn)練后評(píng)分下降,合并后MD=5.27,95%CI(1.97,8.57),Z=3.13(P=0.002)。3個(gè)Meta分析均存在異質(zhì)性,故采用隨機(jī)效應(yīng)模型分析。結(jié)論口咽訓(xùn)練可減低OSAS患者的AHI指數(shù),提高夜間SaO2和改善嗜睡等癥狀,可為患者的康復(fù)提供一種新的無創(chuàng)性治療方法。
[Abstract]:Objective to evaluate the effect of oropharynx training on obstructive sleep apnea syndrome (OSAS) by Meta analysis. After the quality evaluation, the final literature was determined, the relevant index data were extracted and analyzed by RevMan 5.3 software. The results included 6 studies on polysomnography and somnolence, including 92 cases of subjects. Meta analysis showed that, The apnea hypopnea index (AHII) of the patients after oropharyngeal training was significantly lower than that before training, and the mean difference after the combined exercise was 14.2695CII 7.54 ~ 20.98 ~ 4.16p 0.01g. The lowest nocturnal oxygen saturation (SaO2) increased significantly after training. The MD-3.695CI-6.06CI-6.06- 1.2606-2.99g P0.01. Epworth sleepiness scale score showed that. After oropharynx training, the score decreased, and after the combination, the score of MDN 5.27995 CIQ 1.97 / 8.57z3.13P0. 0020.The 3 Meta analysis showed heterogeneity, so the random effect model was used. Conclusion oropharynx training can reduce the AHI index of OSAS patients, increase the nocturnal SaO2 and improve the symptoms of lethargy, etc. It can provide a new non-invasive therapy for the rehabilitation of patients.
【作者單位】: 中山大學(xué)附屬第一醫(yī)院康復(fù)醫(yī)學(xué)科;中山大學(xué)腫瘤防治中心婦科;
【分類號(hào)】:R766;R49
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本文編號(hào):1685798
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