本文關(guān)鍵詞：早產(chǎn)兒感染耐美羅培南肺炎克雷伯菌的危險因素分析　出處：《中華醫(yī)院感染學(xué)雜志》2016年04期 　論文類型：期刊論文

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【摘要】：目的探討早產(chǎn)兒感染耐美羅培南肺炎克雷伯菌的危險因素,從而更有針對性地預(yù)防治療肺炎克雷伯菌感染。方法 2013年3月-2015年3月對醫(yī)院65例早產(chǎn)兒確診感染耐美羅培南肺炎克雷伯菌的臨床資料進行回顧性分析,并與同期住院122例早產(chǎn)兒對美羅培南敏感肺炎克雷伯菌進行比較,對肺炎克雷伯菌醫(yī)院感染的危險因素進行分析。結(jié)果單因素分析顯示,早產(chǎn)兒耐美羅培南肺炎克雷伯菌感染的危險因素包括,出生胎齡、出生體質(zhì)量、住院天數(shù)≥1個月、接受過機械通氣≥5d、經(jīng)外周靜脈穿刺中心靜脈插管、靜脈營養(yǎng)≥2周、使用美羅培南抗菌藥物治療(≥7d)、使用三代頭孢抗菌藥物等,差異有統(tǒng)計學(xué)意義(P0.05);多因素logistic回歸分析發(fā)現(xiàn),使用美羅培南治療(≥7d)為獨立危險因素(OR=2.756,95%CI 1.083~7.014)。結(jié)論根據(jù)藥敏試驗結(jié)果,合理使用抗菌藥物,減少早產(chǎn)兒美羅培南不必要的使用,以減少其耐藥性發(fā)生,有利于控制耐美羅培南肺炎克雷伯菌的傳播。
[Abstract]:Objective to investigate the risk factors of preterm infants infected with Klebsiella pneumoniae resistant to meropenem. Thus more targeted prevention and treatment of Klebsiella pneumoniae infection. From March 2013 to March 2015, the clinical data of 65 preterm infants infected with Klebsiella pneumoniae resistant to meropenem were retrospectively analyzed. The risk factors of nosocomial infection of Klebsiella pneumoniae were analyzed and compared with 122 premature infants in the same period. Results the univariate analysis showed that the risk factors of nosocomial infection of Klebsiella pneumoniae were analyzed. The risk factors of Klebsiella pneumoniae infection in preterm infants included gestational age, birth weight, length of stay 鈮，

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