本文關(guān)鍵詞：蚌埠市維持血液透析患者鈣磷代謝及全段甲狀旁腺激素控制情況橫斷面調(diào)查　出處：《安徽醫(yī)科大學(xué)》2015年碩士論文　論文類型：學(xué)位論文

  更多相關(guān)文章： 血液透析 甲狀旁腺激素 校正血鈣 血磷

【摘要】：目的了解蚌埠市維持性血液透析患者鈣磷代謝及全段甲狀旁腺激素(intact parathyroid hormone,i PTH)控制情況。方法問卷調(diào)查蚌埠市蚌埠醫(yī)學(xué)院第一、第二附屬醫(yī)院血液透析治療大于3個(gè)月的患者,記錄患者一般人口學(xué)資料、原發(fā)病、合并癥、血液透析方式、透析頻率、透析齡,測(cè)定血清鈣、磷及i PTH水平。以2003年KDOQI CKD-MBD指南為依據(jù),分析維持性血液透析患者校正血鈣、血磷、鈣磷乘積和i PTH達(dá)標(biāo)率;同時(shí)分析血清i PTH水平與血紅蛋白(hemoglobin,Hb)、血鈣、血磷、鈣磷乘積等臨床資料相關(guān)性;并分析骨代謝異常并發(fā)臨床癥狀組與無臨床癥狀組、糖尿病腎病組與非糖尿病腎病組臨床資料有無差異。結(jié)果本研究納入170例維持性血液透析患者,校正血鈣、血磷、鈣磷乘積和i PTH的達(dá)標(biāo)率分別為44.7%、44.1%、71.3%和27.6%,上述四項(xiàng)均達(dá)標(biāo)僅5.8%。血清i PTH水平與年齡、血紅蛋白(Hb)及血鈣水平呈負(fù)相關(guān),與血肌酐水平呈正相關(guān)。臨床癥狀組與無臨床癥狀組相比,血鈣、血磷、鈣磷乘積及i PTH均無統(tǒng)計(jì)學(xué)差異。與非糖尿病腎病組相比,糖尿病腎病組i PTH水平低(P=0.014)及血磷較低(P=0.003),但血鈣及鈣磷乘積(P0.05)無差異。結(jié)論蚌埠市維持性血液透析患者血清鈣、磷及i PTH控制不理想;低血鈣、低血紅蛋白水平可能是i PTH升高的危險(xiǎn)因素。
[Abstract]:Objective to understand the Bengbu city to maintain the calcium phosphorus metabolism in hemodialysis patients and intact parathyroid hormone (intact parathyroid hormone, I PTH). The control method of questionnaire survey of Bengbu Medical College in Bengbu city the first, the Second Affiliated Hospital of hemodialysis for more than 3 months were recorded in patients with general demographic data, primary disease, complications, blood dialysis and the frequency of dialysis, dialysis age, serum calcium, phosphorus and I level of PTH. In 2003 KDOQI CKD-MBD guidelines as the basis, analysis of patients with maintenance hemodialysis corrected serum calcium, serum phosphorus, calcium and phosphorus product compliance rate and I PTH; and I analysis of serum PTH levels and hemoglobin (hemoglobin, Hb), blood calcium, blood phosphorus the clinical data, the calcium phosphorus product correlation; and analysis of the patients with abnormal bone metabolism clinical symptom group and asymptomatic group, diabetic nephropathy group had no difference with non diabetic nephropathy group. Results the clinical data The study included 170 cases of hemodialysis patients, correction of calcium, phosphorus, calcium phosphorus product and I PTH compliance rates were 44.7%, 44.1%, 71.3% and 27.6%, the four were only 5.8%. I serum PTH levels and age, hemoglobin (Hb) were negatively correlated and positively correlated with the blood calcium level. Creatinine levels. The clinical symptoms compared with asymptomatic group of calcium, phosphorus, calcium and phosphorus product were no significant difference between I and PTH. Compared with non diabetic nephropathy group, diabetic nephropathy group I low levels of PTH (P=0.014) and low phosphorus (P=0.003), but the level of serum calcium and calcium phosphorus product (P0.05) no difference. Conclusion Bengbu maintaining blood dialysis patients serum calcium, phosphorus and I PTH control is not ideal; low calcium, low hemoglobin level may be a risk factor of I PTH increased.

【學(xué)位授予單位】：安徽醫(yī)科大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2015
【分類號(hào)】：R692.5

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