發(fā)布時間：2018-01-06 12:02

  本文關鍵詞：3.0TMR動態(tài)增強聯(lián)合擴散加權成像在子宮內膜癌術前評估中的價值　出處：《南京醫(yī)科大學學報(自然科學版)》2016年12期 　論文類型：期刊論文

  更多相關文章： 子宮內膜癌 磁共振成像 動態(tài)增強 擴散加權成像 分期

【摘要】：目的 :探討3.0TMR動態(tài)增強掃描(DCE-MRI)聯(lián)合擴散加權成像(DWI)在評估診斷子宮內膜癌患者肌層浸潤深度、宮頸侵犯和術前分期中的應用價值。方法:經病理證實的26例子宮內膜癌患者術前MRI影像資料,包括T_1WI、T_2WI、DCE-MRI和DWI序列,對照術后病理結果,評估應用DCE-MRI、DWI及DCE-MRI聯(lián)合DWI法診斷子宮內膜癌肌層浸潤、宮頸侵犯和術前分期的敏感性、特異性、準確率、陽性預測值、陰性預測值;比較不同成像方法對肌層浸潤、宮頸侵犯和術前分期的準確率。結果:DCE-MRI、DWI及DCE-MRI聯(lián)合DWI法判斷肌層浸潤深度的準確率分別為76.92%、73.08%和84.62%,DCE-MRI聯(lián)合DWI法高于單獨應用DCE-MRI和單獨應用DWI法,差異具有統(tǒng)計學意義(P0.05);DCE-MRI、DWI及DCE-MRI聯(lián)合DWI法判斷宮頸侵犯的準確率分別為76.92%、73.08%和88.46%,DCE-MRI聯(lián)合DWI法高于單獨應用DCE-MRI和單獨應用DWI法,差異具有統(tǒng)計學意義(P0.05);DCE-MRI、DWI及DCE-MRI聯(lián)合DWI法判斷分期的準確率分別為65.38%、53.85%和80.77%,DCEMRI聯(lián)合DWI法高于單獨應用DCE-MRI和單獨應用DWI法,差異具有統(tǒng)計學意義(P0.05)。結論 :聯(lián)合應用DCE-MRI和DWI較單獨應用DCE-MRI或DWI可以更準確地進行子宮內膜癌術前評估,應常規(guī)應用于子宮內膜癌的術前檢查。
[Abstract]:Objective: To investigate the dynamic enhanced 3.0TMR (DCE-MRI) combined with diffusion weighted imaging (DWI) in diagnosis of patients with endometrial carcinoma muscle layer infiltration depth, application value in staging and preoperative cervical invasion. Methods: 26 patients with pathologically confirmed endometrial cancer patients preoperative MRI image data, including T_1WI and T_2WI. DCE-MRI and DWI sequence, compared with postoperative pathological results, evaluate the application of DCE-MRI, DWI and DCE-MRI combined with DWI method for diagnosis of myometrial invasion of endometrial carcinoma, the sensitivity, the staging of cervical invasion and preoperative specificity, accuracy, positive predictive value, negative predictive value; comparison of different imaging methods on the infiltration of the muscle layer, accuracy the staging of cervical invasion and before surgery. Results: DCE-MRI, DWI and DCE-MRI combined with DWI method to determine the depth of myometrial invasion accuracy were 76.92%, 73.08% and 84.62%, DCE-MRI combined with DWI was significantly higher than that of DCE-MRI alone and DWI alone, the difference There was statistical significance (P0.05); DCE-MRI, DWI and DCE-MRI combined with DWI method to judge the accuracy of cervical invasion were 76.92%, 73.08% and 88.46%, DCE-MRI combined with DWI was significantly higher than that of DCE-MRI alone and DWI alone, the difference was statistically significant (P0.05); DCE-MRI, DWI and DCE-MRI combined with DWI method to determine the accuracy rate of staging were 65.38%, 53.85% and 80.77%, DCEMRI combined with DWI was significantly higher than that of DCE-MRI alone and DWI alone, the difference was statistically significant (P0.05). Conclusion: the combined application of DCE-MRI and DWI compared with the single application of DCE-MRI or DWI can evaluate the endometrial cancer to more accurately before, should check the routine application in endometrial carcinoma before the operation.

【作者單位】： 徐州醫(yī)科大學附屬連云港醫(yī)院影像科;
【分類號】：R445.2
【正文快照】： 子宮內膜癌是女性生殖系統(tǒng)常見的惡性腫瘤之一[1],其組織學類型、腫瘤病理分級,尤其是對子宮肌層浸潤深度及宮頸侵犯情況與治療方案的制定及患者的預后密切相關[2]。因此術前對子宮內膜癌進行準確評估意義重大。動態(tài)增強磁共振成像(dynamic contrast-enhanced MRI,DCE-MRI)和

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