發(fā)布時(shí)間：2018-01-06 12:02

  本文關(guān)鍵詞：3.0TMR動(dòng)態(tài)增強(qiáng)聯(lián)合擴(kuò)散加權(quán)成像在子宮內(nèi)膜癌術(shù)前評(píng)估中的價(jià)值　出處：《南京醫(yī)科大學(xué)學(xué)報(bào)(自然科學(xué)版)》2016年12期 　論文類型：期刊論文

  更多相關(guān)文章： 子宮內(nèi)膜癌 磁共振成像 動(dòng)態(tài)增強(qiáng) 擴(kuò)散加權(quán)成像 分期

【摘要】：目的 :探討3.0TMR動(dòng)態(tài)增強(qiáng)掃描(DCE-MRI)聯(lián)合擴(kuò)散加權(quán)成像(DWI)在評(píng)估診斷子宮內(nèi)膜癌患者肌層浸潤(rùn)深度、宮頸侵犯和術(shù)前分期中的應(yīng)用價(jià)值。方法:經(jīng)病理證實(shí)的26例子宮內(nèi)膜癌患者術(shù)前MRI影像資料,包括T_1WI、T_2WI、DCE-MRI和DWI序列,對(duì)照術(shù)后病理結(jié)果,評(píng)估應(yīng)用DCE-MRI、DWI及DCE-MRI聯(lián)合DWI法診斷子宮內(nèi)膜癌肌層浸潤(rùn)、宮頸侵犯和術(shù)前分期的敏感性、特異性、準(zhǔn)確率、陽性預(yù)測(cè)值、陰性預(yù)測(cè)值;比較不同成像方法對(duì)肌層浸潤(rùn)、宮頸侵犯和術(shù)前分期的準(zhǔn)確率。結(jié)果:DCE-MRI、DWI及DCE-MRI聯(lián)合DWI法判斷肌層浸潤(rùn)深度的準(zhǔn)確率分別為76.92%、73.08%和84.62%,DCE-MRI聯(lián)合DWI法高于單獨(dú)應(yīng)用DCE-MRI和單獨(dú)應(yīng)用DWI法,差異具有統(tǒng)計(jì)學(xué)意義(P0.05);DCE-MRI、DWI及DCE-MRI聯(lián)合DWI法判斷宮頸侵犯的準(zhǔn)確率分別為76.92%、73.08%和88.46%,DCE-MRI聯(lián)合DWI法高于單獨(dú)應(yīng)用DCE-MRI和單獨(dú)應(yīng)用DWI法,差異具有統(tǒng)計(jì)學(xué)意義(P0.05);DCE-MRI、DWI及DCE-MRI聯(lián)合DWI法判斷分期的準(zhǔn)確率分別為65.38%、53.85%和80.77%,DCEMRI聯(lián)合DWI法高于單獨(dú)應(yīng)用DCE-MRI和單獨(dú)應(yīng)用DWI法,差異具有統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論 :聯(lián)合應(yīng)用DCE-MRI和DWI較單獨(dú)應(yīng)用DCE-MRI或DWI可以更準(zhǔn)確地進(jìn)行子宮內(nèi)膜癌術(shù)前評(píng)估,應(yīng)常規(guī)應(yīng)用于子宮內(nèi)膜癌的術(shù)前檢查。
[Abstract]:Objective: To investigate the dynamic enhanced 3.0TMR (DCE-MRI) combined with diffusion weighted imaging (DWI) in diagnosis of patients with endometrial carcinoma muscle layer infiltration depth, application value in staging and preoperative cervical invasion. Methods: 26 patients with pathologically confirmed endometrial cancer patients preoperative MRI image data, including T_1WI and T_2WI. DCE-MRI and DWI sequence, compared with postoperative pathological results, evaluate the application of DCE-MRI, DWI and DCE-MRI combined with DWI method for diagnosis of myometrial invasion of endometrial carcinoma, the sensitivity, the staging of cervical invasion and preoperative specificity, accuracy, positive predictive value, negative predictive value; comparison of different imaging methods on the infiltration of the muscle layer, accuracy the staging of cervical invasion and before surgery. Results: DCE-MRI, DWI and DCE-MRI combined with DWI method to determine the depth of myometrial invasion accuracy were 76.92%, 73.08% and 84.62%, DCE-MRI combined with DWI was significantly higher than that of DCE-MRI alone and DWI alone, the difference There was statistical significance (P0.05); DCE-MRI, DWI and DCE-MRI combined with DWI method to judge the accuracy of cervical invasion were 76.92%, 73.08% and 88.46%, DCE-MRI combined with DWI was significantly higher than that of DCE-MRI alone and DWI alone, the difference was statistically significant (P0.05); DCE-MRI, DWI and DCE-MRI combined with DWI method to determine the accuracy rate of staging were 65.38%, 53.85% and 80.77%, DCEMRI combined with DWI was significantly higher than that of DCE-MRI alone and DWI alone, the difference was statistically significant (P0.05). Conclusion: the combined application of DCE-MRI and DWI compared with the single application of DCE-MRI or DWI can evaluate the endometrial cancer to more accurately before, should check the routine application in endometrial carcinoma before the operation.

【作者單位】： 徐州醫(yī)科大學(xué)附屬連云港醫(yī)院影像科;
【分類號(hào)】：R445.2
【正文快照】： 子宮內(nèi)膜癌是女性生殖系統(tǒng)常見的惡性腫瘤之一[1],其組織學(xué)類型、腫瘤病理分級(jí),尤其是對(duì)子宮肌層浸潤(rùn)深度及宮頸侵犯情況與治療方案的制定及患者的預(yù)后密切相關(guān)[2]。因此術(shù)前對(duì)子宮內(nèi)膜癌進(jìn)行準(zhǔn)確評(píng)估意義重大。動(dòng)態(tài)增強(qiáng)磁共振成像(dynamic contrast-enhanced MRI,DCE-MRI)和

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