本文選題：疫苗 + 科學(xué)監(jiān)管�。� 參考：《中國新藥雜志》2017年20期

【摘要】：疫苗儲存運輸要遵循冷鏈運輸(cold chain,CC)的要求,這很大程度上限制了疫苗的接種和普及,尤其是在那些貧困偏遠地區(qū)。為擴大疫苗可及性,世界衛(wèi)生組織(World Health Organization,WHO)于2012年首次提出了受控溫度鏈(controlled temperature chain,CTC)法規(guī),即在政府部門和WHO的監(jiān)管下,在有充分熱穩(wěn)定性數(shù)據(jù)支持的前提下,若申報CTC的疫苗在不低于40℃下存放至少3 d后仍能保證效力,則該疫苗在免疫供應(yīng)鏈后期無需冷鏈運輸。CTC法規(guī)已成功應(yīng)用在包括MenAfriVac汶在內(nèi)的4個商品化疫苗上。本文介紹了CTC法規(guī)的內(nèi)容和應(yīng)用情況,通過科學(xué)監(jiān)管提高疫苗可及性,減少不必要的浪費。
[Abstract]:Storage and transportation of vaccines follow the requirements of cold chain transport of cold chain CCs, which greatly limits vaccination and access, especially in poor and remote areas. In order to expand vaccine accessibility, the World Health Organization (WHO) first introduced the controlled temperature chain in 2012, which is supported by adequate thermal stability data under the supervision of government departments and WHO. If the CTC vaccine is kept at 40 鈩，

本文編號：1832677