【摘要】：隨著現(xiàn)代科技的快速發(fā)展,高頻超聲在科研和工業(yè)領(lǐng)域,如超聲醫(yī)療檢測(cè)、超聲無損檢測(cè)等領(lǐng)域的應(yīng)用日益成熟。利用聲輻射力實(shí)現(xiàn)生物醫(yī)學(xué)領(lǐng)域?qū)崿F(xiàn)細(xì)胞篩選、藥物輸送作用,以及在工業(yè)設(shè)計(jì)領(lǐng)域?qū)崿F(xiàn)微粒子的非接觸操控等,是目前醫(yī)學(xué)超聲研究熱點(diǎn)之一,聲波對(duì)球粒子的聲輻射力研究對(duì)新型聲鑷子的設(shè)計(jì)具有重要的現(xiàn)實(shí)意義。本論文利用聲散射理論方法對(duì)聲波作用于球形粒子的聲輻射力的特性進(jìn)行了研究。第一章的主要內(nèi)容是回顧了聲輻射力相關(guān)的理論研究和實(shí)際應(yīng)用歷史,介紹了近期有關(guān)聲輻射力的研究進(jìn)展,并概述了本文研究工作的主要內(nèi)容,接著介紹基于球散射理論的聲輻射力計(jì)算方法。第二章主要介紹基于點(diǎn)聲源的球散射理論下中空聚焦換能器對(duì)軸向球粒子的聲輻射力。在未考慮聲衰減前提下,仿真結(jié)果證明中空聚焦換能器在近場(chǎng)區(qū)域產(chǎn)生了聲輻射拉力區(qū),聲輻射拉力區(qū)域與內(nèi)、外角以及完全硬介質(zhì)球半徑大小有關(guān)。該結(jié)論可能對(duì)未來單聲源聲鑷子的實(shí)現(xiàn)具有理論指導(dǎo)意義。第三章主要介紹基于球聲散射理論下環(huán)狀換能器中軸線上的球所受聲輻射力的模型。未考慮介質(zhì)中聲傳播損耗的前提下,計(jì)算結(jié)果發(fā)現(xiàn)環(huán)狀換能器軸向的近場(chǎng)區(qū)域存在聲輻射拉力區(qū)域,該區(qū)域與納米量級(jí)球的大小材質(zhì)、距離、內(nèi)外半徑的大小等相關(guān),本章重點(diǎn)討論聲輻射拉力區(qū)與上述因素的關(guān)系。研究結(jié)果對(duì)聲鑷子的研究制作具有指導(dǎo)作用。第四章主要利用有限級(jí)數(shù)展開的方法,通過將貝塞爾高斯波進(jìn)行球函數(shù)展開計(jì)算了波束因子,推導(dǎo)出貝塞爾高斯波對(duì)軸向上粒子的聲輻射力,拓展了貝塞爾波的聲輻射力研究。為未來利用單向非衍射波實(shí)現(xiàn)聲捕獲提供理論基礎(chǔ)。本文建立各種不同聲場(chǎng)中聲輻射力模型,計(jì)算了球形粒子在不同單聲源中受到的聲輻射力,對(duì)單聲源聲鑷子的設(shè)計(jì)制作,實(shí)現(xiàn)工業(yè)和醫(yī)學(xué)上的無損操控有著重要的理論指導(dǎo)作用
[Abstract]:With the rapid development of modern science and technology, the application of high frequency ultrasound in the fields of scientific research and industry, such as ultrasonic medical testing, ultrasonic nondestructive testing and so on, has become increasingly mature. The use of acoustic radiation to realize cell screening, drug delivery, and non-contact manipulation of microparticles in the field of industrial design is one of the hot spots in the field of medical ultrasound. The study of acoustic radiation force on ball particles is of great practical significance for the design of new type tweezers. In this paper, the acoustic radiation force of spherical particles is studied by means of acoustic scattering theory. The main contents of the first chapter are to review the theoretical research and practical application history of acoustic radiation force, introduce the recent research progress of acoustic radiation force, and summarize the main contents of the research work in this paper. Then the calculation method of acoustic radiation force based on sphere scattering theory is introduced. In the second chapter, the acoustic radiation force of the hollow focusing transducer on the axial spherical particles based on the point sound source theory is introduced. Without considering the sound attenuation, the simulation results show that the hollow focusing transducer produces the sound radiative force region in the near field, which is related to the size of the inner, outer angle and the radius of the complete hard medium sphere. This conclusion may be of theoretical significance for the realization of mono-source tweezers in the future. In chapter 3, the model of sound radiation force on the axis of ring transducer based on the theory of spherical sound scattering is introduced. Without considering the sound propagation loss in the medium, the calculation results show that there is a region of acoustic radiation force in the axial region of the annular transducer, which is related to the material size, distance and radius of the nanoscale ball, etc. This chapter focuses on the relationship between the acoustic radiation tension region and the above factors. The results can be used to guide the research and manufacture of tweezers. In chapter 4, by using the method of finite series expansion, the beam-factor is calculated by using the spherical function expansion of Bessel Goss wave, and the acoustic radiation force of Bessel Goss wave on the axial particle is deduced, which extends the study of acoustic radiation force of Bessel wave. It provides a theoretical basis for acoustic capture using unidirectional nondiffractive waves in the future. In this paper, various sound radiation force models in different sound fields are established, and the sound radiation forces of spherical particles in different mono sound sources are calculated. It has important theoretical guidance for the design and manufacture of single sound source tweezers and the realization of nondestructive manipulation in industry and medicine.
【學(xué)位授予單位】：南京大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2017
【分類號(hào)】：TB552
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本文編號(hào)：2258609