本文關(guān)鍵詞：甘草及其活性成分抗炎與抗炎機(jī)制的研究進(jìn)展，，由筆耕文化傳播整理發(fā)布。

現(xiàn)代藥物與臨床 Drugs & Clinic 第 26 卷 第 4 期 2011 年 7 月 ? 261 ? 甘草及其活性成分抗炎與抗炎機(jī)制的研究進(jìn)展 張明發(fā)，沈雅琴 上海美優(yōu)制藥有限公司，上海 201422 摘 要：甘草及其活性成分能提高吞噬細(xì)胞的吞噬功能、調(diào)節(jié)淋巴細(xì)胞數(shù)量與功能、抑制 IgE 抗體形成、抗炎癥介質(zhì)及前炎 性細(xì)胞因子，具有抗炎、抗變態(tài)反應(yīng)的藥理活性。甘草黃酮類化合物（異甘草素、異甘草苷、甘草素、甘草查耳酮 A 、光甘 草定、甘草醇等）、甘草多糖和甘草酸是其抗炎、抗變應(yīng)性炎癥的活性成分。其中對(duì)異甘草素、甘草查耳酮A 和甘草酸的抗 炎及抗變應(yīng)性炎癥作用的研究較為深入。綜述甘草及其活性成分的抗炎作用及抗炎機(jī)制的研究進(jìn)展。 關(guān)鍵詞：甘草；甘草黃酮類；甘草多糖；甘草查耳酮 A ；抗炎 中圖分類號(hào)：R285.5 ；R282.71 文獻(xiàn)標(biāo)志碼：A 文章編號(hào)：1674 - 5515 2011 04- 0261 - 08 Advances in studies on Glycyrrhizae Radix et Rhizoma and its active components in anti-inflammation and mechanism ZHANG Ming-fa, SHEN Ya-qin Shanghai Meiyou Pharmaceutical Co., Ltd., Shanghai 201422, China Abstract: Glycyrrhizae Radix et Rhizoma and its active components can enhance the phagocytic function of phagocytes, modulate the quantity and function of lymphocytes, inhibit the antibody formation of IgE, possess the effects against inflammatory mediator and proinflammatory cytokines, and induce pharmacologic activities against inflammation and allergy. Flavonoids isoliquiritigenin, isoliquiritin, liquiritigenin, licochalcone A, glabridin, glycyrol, and so on , glycyrrhiza polysaccharide and glycyrrhizic acid are active components of Glycyrrhizae Radix et Rhizoma on anti-inflammation and immunoregulation. Among others, the anti-inflammation and anti-allergy of isoliquiritigenin, licochalcone

  本文關(guān)鍵詞：甘草及其活性成分抗炎與抗炎機(jī)制的研究進(jìn)展，由筆耕文化傳播整理發(fā)布。