【摘要】：目的：評價辨證針刺治療脾胃氣虛型餐后不適綜合征(Postprandial Distress Syndrome, PDS)的臨床療效,在研究人口學特征與疾病的相關(guān)性的基礎(chǔ)上,探討人口學特征對針刺效應(yīng)的影響,為辨證針刺治療PDS的臨床運用提供研究依據(jù)。方法：1、采用隨機對照的研究方法,將97例PDS患者隨機分為A組(辨證針刺組)、B組(非經(jīng)非穴組),根據(jù)不同取穴方案,每組受試者每日接受1次時長30分鐘的電針治療,共20次,以尼平消化不良指數(shù)(Nepean Dyspepsia Index, NDI)的癥狀積分表和生活質(zhì)量評分表為評價指標,分別于入組時、治療結(jié)束、結(jié)束后4周隨訪時評價兩組治療對PDS患者癥狀和生活質(zhì)量(Quality of life, QoL)的影響。2、在搜集97例脾胃氣虛型PDS受試者的基線資料,通過對基線數(shù)據(jù)的統(tǒng)計分析,分析其人口學特點的基礎(chǔ)上,采用相關(guān)性分析,探討PDS患者人口學特征對針刺效應(yīng)的影響。結(jié)果：1、辨證針刺治療PDS的臨床療效評價(1)針刺治療對PDS患者癥狀的影響：組內(nèi)比較的結(jié)果顯示：與針刺前相比,辨證針刺組在治療后與隨訪時都呈現(xiàn)了統(tǒng)計學差異(P=0.000)：非經(jīng)非穴組在治療后與隨訪時也都呈現(xiàn)了統(tǒng)計學差異(P=0.000)。組間比較的結(jié)果顯示：與非經(jīng)非穴組相比,辨證針刺在入組第4周至第8周之間,均可以顯著降低患者上腹部不適、餐后脹滿或消化緩慢、腹部脹氣、惡心的癥狀評分,差異具有統(tǒng)計學意義(P0.05)；(2)針刺治療對PDS患者生活質(zhì)量的影響：組內(nèi)比較的結(jié)果顯示：與針刺前相比,辨證針刺組在治療后與隨訪時都呈現(xiàn)了統(tǒng)計學差異(P=0.000)；非經(jīng)非穴組在治療后與隨訪時也都呈現(xiàn)了統(tǒng)計學差異(P=0.000)。組間比較的結(jié)果顯示：與非經(jīng)非穴組相比,辨證針刺在入組第4周至第8周之間可以顯著改善NDI生活質(zhì)量評分量表干擾領(lǐng)域、認識和控制領(lǐng)域、食物飲料領(lǐng)域、睡眠領(lǐng)域四個領(lǐng)域的評分,差異具有統(tǒng)計學意義(P0.05)。2、人口學特征對針刺治療PDS療效影響研究(1)PDS患者的人口學特點及其與疾病的相關(guān)性在所有受試者中,性別上：女性患者占比重較大；年齡上：青年患者占比重較大；職業(yè)和教育上：高學歷患者、職員和學生占比例較大,均具有統(tǒng)計學差異(P0.05)；年齡與上腹部不適、不按規(guī)律進餐和睡眠領(lǐng)域的評分具有顯著相關(guān)性,有統(tǒng)計學意義(P0.05)。(2)年齡對針刺治療PDS療效的影響治療后,以老年人為對照,青年人和中年人的P值分別為0.011和0.032；在第8周時,青年人和中年人的P值為0.015和0.229,兩組均具有統(tǒng)計學差異(P0.05)。結(jié)論：1、辨證針刺治療脾胃氣虛型PDS療效優(yōu)于非經(jīng)非穴,辨證針刺和非經(jīng)非穴均能明顯改善受試者的癥狀和生活質(zhì)量。2、年齡和性別是PDS發(fā)病的重要影響因素,年輕人和女性更容易患PDS,其原因與教育、職業(yè)以及性別生理差異有關(guān),并且年齡與上腹部不適、不能按規(guī)律進餐的癥狀評分呈正相關(guān)關(guān)系。3、年齡是影響針刺治療PDS療效的因素。
[Abstract]:Objective: to evaluate the clinical effect of syndrome differentiation acupuncture on postmeal discomfort syndrome (Postprandial Distress Syndrome, PDS) with spleen and stomach qi deficiency type, and to explore the influence of demographic characteristics on acupuncture effect on the basis of studying the correlation between demographic characteristics and diseases, so as to provide research basis for clinical application of syndrome differentiation acupuncture in the treatment of PDS. Methods: 1. 97 patients with PDS were randomly divided into group A (syndrome differentiation acupuncture group), B group). According to different acupoint selection schemes, each group received 30 minutes of electro-acupuncture treatment once a day for 20 times. The symptom score table and quality of life score table of niping dyspepsia index (Nepean Dyspepsia Index, NDI) were used as evaluation indexes, and the treatment ended at the time of admission. The effects of treatment on symptoms and quality of life (Quality of life, QoL) of PDS patients were evaluated at 4 weeks after follow-up. 2. Based on the collection of baseline data of 97 PDS subjects with spleen and stomach qi deficiency type, the demographic characteristics of PDS patients were analyzed by statistical analysis, and the effect of demographic characteristics on acupuncture effect was discussed by correlation analysis. Results: 1. Evaluation of clinical efficacy of syndrome differentiation acupuncture in the treatment of PDS (1) the effect of acupuncture treatment on the symptoms of PDS patients: the results of intra-group comparison showed that compared with before acupuncture, there was significant difference after treatment and follow-up in syndrome differentiation acupuncture group (P 鈮，

本文編號：2504142