【摘要】：目的:觀察疏肝利膽活血法治療慢性乙型病毒性肝炎合并慢性膽囊炎的臨床療效,為臨床研究和治療提供參考。方法:選取江蘇省中醫(yī)院感染科門診確診為慢性乙型病毒型肝炎合并慢性膽囊炎、中醫(yī)辯證分型為氣滯血瘀型的患者60例,分為治療組和對照組各30例,治療組予中醫(yī)疏肝利膽活血法治療,對照組予口服茴三硫膠囊(每次1粒,每日3次),以4周為1個(gè)療程,治療4周、8周后觀察兩組患者的臨床癥狀、實(shí)驗(yàn)室檢查結(jié)果及超聲影像學(xué),利用統(tǒng)計(jì)學(xué)軟件對其結(jié)果進(jìn)行比較研究。結(jié)果:(1)癥狀比較:組內(nèi)比較,治療4周后與治療前、治療8周后與治療前、治療8周后與治療4周后相比,治療組與對照組癥狀總積分明顯改善(P0.05),單項(xiàng)癥狀右脅疼痛、口苦咽干明顯改善(P0.05)。組間比較,治療8周后,治療組在改善癥狀總積分方面明顯優(yōu)于對照組(P0.05),在改善右脅疼痛、口苦咽干、胸悶太息、右脅痛夜間加重方面明顯優(yōu)于對照組(P0.05)。(2)實(shí)驗(yàn)室檢查比較:組內(nèi)比較,治療4周后與治療前、治療8周后與治療前、治療8周后與治療4周后相比,治療組與對照組AKP、GGT明顯改善(P0.05)。組間比較,治療8周后,治療組改善AKP、GGT與對照組療效相當(dāng)(P0.05)。(3)B超檢查比較:組內(nèi)比較,治療8周后與治療4周后相比,治療組膽囊壁增厚、膽汁透聲差明顯改善(P0.05)。組間比較,治療8周后,治療組對膽壁毛糙、膽汁透聲差改善效果明顯優(yōu)于對照組(P0.05)。結(jié)論:疏肝利膽活血法治療慢性乙型病毒性肝炎合并慢性膽囊炎氣滯血瘀型患者,能改善患者的臨床癥狀、肝功能、B超檢查結(jié)果,尤其在右脅疼痛、右脅痛夜間加重、口苦咽干、胸悶太息癥狀及B超檢查中膽壁毛糙、膽汁透聲方面的改善有優(yōu)勢,延長使用時(shí)間可提高治療效果;對于治療慢乙肝合并膽囊炎的長期療效,以及對病情的根本改善是否有效還需要進(jìn)一步研究。
[Abstract]:Objective: To observe the clinical effect of dispersing stagnated liver-qi and promoting blood circulation in the treatment of chronic viral hepatitis B with chronic cholecystitis and to provide reference for clinical research and treatment. Methods:60 patients with chronic hepatitis B combined with chronic cholecystitis and traditional Chinese medicine were divided into treatment group and control group. The clinical symptoms, laboratory findings and ultrasonic imaging of the two groups were observed after 4 weeks and 8 weeks in the control group. The results of the two groups were compared and studied by using the statistical software. Results: (1) The symptoms of the treatment group and the control group were significantly improved after 4 weeks of treatment and 4 weeks after the treatment (P0.05). There was a significant improvement in the dry throat (P0.05). Compared with the control group (P0.05), the treatment group was better than the control group (P0.05) in the treatment group after 8 weeks of treatment, and it was better than the control group (P0.05). (2) Compared with the control group, the treatment group and the control group AKP and GGT were significantly improved after 8 weeks of treatment and 4 weeks after the treatment (P0.05). After 8 weeks of treatment, the treatment group improved the effect of AKP and GGT in the control group (P0.05). (3) The comparison of B-ultrasound examination: compared with the treatment group, the gallbladder wall of the treatment group was thickened and the sound of the bile was significantly improved after 8 weeks of treatment (P0.05). After 8 weeks of treatment, the treatment group was better than the control group after 8 weeks of treatment (P0.05). Conclusion: The treatment of chronic viral hepatitis B with qi stagnation and blood stasis with the effect of dispersing stagnated liver-energy and promoting blood circulation can improve the clinical symptoms, liver function and B-ultrasonic examination of patients. Especially in the right and hypochondrium, the right hand pain is aggravated at night and the mouth is bitter and dry. The symptoms of chest distress and the symptoms of the gallbladder wall in the B-mode ultrasound examination have the advantages of improving the use time and improving the treatment effect, and further research is needed for the long-term curative effect of the treatment of the chronic hepatitis B and the cholecystitis, and whether the fundamental improvement of the condition is effective.
【學(xué)位授予單位】：南京中醫(yī)藥大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2017
【分類號】：R259

【參考文獻(xiàn)】

相關(guān)期刊論文 前10條

1 李偉;;大柴胡湯對膽結(jié)石合并慢性膽囊炎圍手術(shù)期患者的影響[J];吉林中醫(yī)藥;2016年12期

2 韓紹騰;;腹腔鏡膽囊切除術(shù)并發(fā)癥及防范對策研究[J];當(dāng)代醫(yī)學(xué);2016年34期

3 蒲新宇;謝晶日;;謝晶日教授治療慢性膽囊炎[J];吉林中醫(yī)藥;2016年11期

4 葛政;李鑫浩;程佼佼;;李應(yīng)存教授運(yùn)用敦煌大瀉肝湯治療慢性膽囊炎經(jīng)驗(yàn)[J];中醫(yī)研究;2016年11期

5 李陽;;疏肝健脾法治療慢性乙型病毒性肝炎的臨床效果分析[J];大家健康(學(xué)術(shù)版);2016年08期

6 鐘蕊;陳煜;;片仔癀治療慢性乙型肝炎合并膽囊炎的臨床研究[J];大家健康(學(xué)術(shù)版);2016年06期

7 李正軍;郭冰;李淑玲;劉國安;;劉國安教授治療慢性膽囊炎臨床經(jīng)驗(yàn)[J];西部中醫(yī)藥;2016年02期

8 段曉芳;;柴胡疏肝散加減治療慢性膽囊炎的臨床療效觀察[J];臨床合理用藥雜志;2015年35期

9 陳沁磊;邵銘;胡謙鋒;;邵銘教授治療膽系疾病[J];吉林中醫(yī)藥;2015年12期

10 陳麗;;小柴胡湯加減治療慢性膽囊炎104例療效分析[J];中醫(yī)臨床研究;2015年31期

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