【摘要】：目的:觀察壯醫(yī)藥線點(diǎn)灸結(jié)合西醫(yī)常規(guī)療法治療尋常型銀屑病的臨床療效及安全性,為臨床上使用該療法治療尋常型銀屑病提供依據(jù)。方法:首先采用隨機(jī)數(shù)字表法,將50例尋常型銀屑病患者隨機(jī)分為試驗(yàn)組25例,對照組25例。對照組采用西醫(yī)常規(guī)療法治療,療程30天。試驗(yàn)組在對照組的治療基礎(chǔ)上加用壯醫(yī)藥線點(diǎn)灸療法治療,壯醫(yī)藥線點(diǎn)灸療法隔天治療1次,共治療15次。療程結(jié)束后,對皮損面積和嚴(yán)重程度(PASI)進(jìn)行療效評(píng)價(jià),對瘙癢等級(jí)、皮膚病生活質(zhì)量指數(shù)量表(DLQI)、漢密頓焦慮量表(HAMA)(包括焦慮心境、緊張、失眠等)進(jìn)行評(píng)價(jià)分析。采用實(shí)驗(yàn)室安全性評(píng)價(jià)指標(biāo)及不良事件發(fā)生情況對結(jié)局進(jìn)行安全性評(píng)價(jià)。結(jié)果:經(jīng)30天治療后,兩組各有25例完成試驗(yàn)。試驗(yàn)組達(dá)到臨床治愈的0例、顯效13例、有效9例、無效3例,有效率88%;對照組達(dá)到臨床治愈的0例、顯效4例、有效10例、無效11例,有效率56%。兩組有效率比較,差異有統(tǒng)計(jì)學(xué)意義(P0.05)。在改善患者皮損面積和嚴(yán)重程度、減輕瘙癢、緩解焦慮、提高患者生活質(zhì)量方面,試驗(yàn)組優(yōu)于對照組,兩組差異有顯著統(tǒng)計(jì)學(xué)意義(P0.01);兩組均未出現(xiàn)安全性指標(biāo)異常。對照組1例患者出現(xiàn)輕微惡心、腹瀉;試驗(yàn)組1例患者點(diǎn)灸一段時(shí)間后點(diǎn)灸局部出現(xiàn)淺表的灼傷痕跡伴瘙癢,癥狀輕微。結(jié)論:壯醫(yī)藥線點(diǎn)灸結(jié)合西醫(yī)常規(guī)療法治療尋常型銀屑病在改善患者皮損面積和嚴(yán)重程度、減輕瘙癢、緩解焦慮、提高患者生活質(zhì)量等方面的臨床療效,優(yōu)于單獨(dú)使用西醫(yī)常規(guī)療法,且無明顯不良反應(yīng)及毒副作用,安全性高。
[Abstract]:Objective: to observe the clinical efficacy and safety of Zhuang medicine line moxibustion combined with routine western medicine therapy in the treatment of psoriasis vulgaris, and to provide evidence for clinical use of this therapy in the treatment of psoriasis vulgaris. Methods: 50 patients with psoriasis vulgaris were randomly divided into experimental group (n = 25) and control group (n = 25). The control group was treated with routine western medicine for 30 days. On the basis of the treatment of the control group, the experimental group was treated with Zhuang medicine line moxibustion therapy, and Zhuang medicine line moxibustion therapy was treated once every other day for a total of 15 times. At the end of the course of treatment, the curative effect of (PASI) on skin lesion area and severity was evaluated. For pruritus grade, skin disease quality of life index scale (DLQI), Hamilton anxiety scale (HAMA) (, including anxiety mood, tension. Insomnia, etc.) for evaluation and analysis. The safety evaluation index of laboratory and the occurrence of adverse events were used to evaluate the safety of the outcome. Results: after 30 days of treatment, 25 cases in each group completed the trial. In the experimental group, 0 cases were clinically cured, 13 cases were markedly effective, 9 cases were effective, 3 cases were ineffective, the effective rate was 88%, while in the control group, 0 cases were clinically cured, 4 cases were markedly effective, 10 cases were effective, 11 cases were ineffective, the effective rate was 56%. There was significant difference in the effective rate between the two groups (P 0.05). The experimental group was superior to the control group in improving the area and severity of skin lesions, reducing pruritus, relieving anxiety and improving the quality of life of the patients, and there was significant difference between the two groups (P 0.01). There was no abnormal safety index between the two groups. One patient in the control group had slight nausea and diarrhea, and one patient in the experimental group had superficial burn marks with pruritus after moxibustion for a period of time, and the symptoms were mild. Conclusion: Zhuang medicine line moxibustion combined with routine western medicine therapy in the treatment of psoriasis vulgaris is effective in improving the area and severity of skin lesions, reducing pruritus, relieving anxiety and improving the quality of life of patients. It is superior to routine western medicine alone, and has no obvious adverse reactions and side effects, and has high safety.
【學(xué)位授予單位】：廣西中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2017
【分類號(hào)】：R29

【參考文獻(xiàn)】

相關(guān)期刊論文 前10條

1 陳攀;林辰;方剛;潘利鋒;;壯醫(yī)藥線點(diǎn)灸對帶狀皰疹后神經(jīng)痛患者p38 MAPK基因表達(dá)的影響[J];中華中醫(yī)藥雜志;2016年01期

2 陳樺;唐漢慶;鄭建宇;趙玉峰;莫小強(qiáng);李克明;李曉華;竇錫彬;舒方義;;針刺聯(lián)合壯醫(yī)藥線點(diǎn)灸對睡眠剝奪大鼠相關(guān)神經(jīng)遞質(zhì)的影響[J];世界科學(xué)技術(shù)-中醫(yī)藥現(xiàn)代化;2015年10期

3 唐漢慶;鄭建宇;竇錫彬;李克明;趙玉峰;李曉華;舒方義;廉春容;楊園園;;壯醫(yī)藥線點(diǎn)灸聯(lián)合針挑療法對大鼠抗氧化損傷與衰老的影響[J];中國老年學(xué)雜志;2015年16期

4 劉東華;吳椋冰;蘇強(qiáng);;壯醫(yī)藥線點(diǎn)灸治療年輕士兵急性濕疹的療效觀察[J];人民軍醫(yī);2015年05期

5 唐漢慶;李克明;鄭建宇;竇錫彬;李曉華;趙玉峰;舒方義;廉春容;楊園園;;壯醫(yī)藥線點(diǎn)灸聯(lián)合針挑療法對血管氧化應(yīng)激損傷的影響[J];針刺研究;2015年01期

6 曾均;;升陽散火湯配合壯醫(yī)藥線點(diǎn)灸治療尋常痤瘡80例[J];實(shí)用中醫(yī)藥雜志;2014年12期

7 滕紅麗;鄧娟娟;;壯醫(yī)藥線點(diǎn)灸綜合治療白癜風(fēng)的技術(shù)規(guī)范研究[J];中國民族民間醫(yī)藥;2014年21期

8 覃興樂;黃岑漢;徐森明;農(nóng)小珍;;壯醫(yī)藥線點(diǎn)灸治療Ⅲ期褥瘡的臨床療效觀察[J];中國民間療法;2014年10期

9 杜艷;黃月蓮;韋日鋪;吳海標(biāo);;壯醫(yī)藥線點(diǎn)灸配合針刺治療帶狀皰疹后遺神經(jīng)痛的優(yōu)化方案研究[J];遼寧中醫(yī)雜志;2014年08期

10 馬玲;陸勁;;朱璉抑制手法結(jié)合壯醫(yī)藥線點(diǎn)灸治療帶狀皰疹后遺神經(jīng)痛療效觀察[J];右江民族醫(yī)學(xué)院學(xué)報(bào);2014年03期

相關(guān)會(huì)議論文 前2條

1 李紅;;壯醫(yī)藥線點(diǎn)灸配合腹針治療頑固性濕疹臨床體會(huì)[A];首屆全國腹針學(xué)術(shù)研討會(huì)會(huì)議論文集[C];2007年

2 郭曉樂;王富春;;三陰交穴的臨床應(yīng)用概況[A];中國針灸學(xué)會(huì)針推結(jié)合專業(yè)委員會(huì)成立大會(huì)暨針灸教育與腧穴應(yīng)用學(xué)術(shù)研討會(huì)論文匯編[C];2010年

相關(guān)重要報(bào)紙文章 前1條

1 滕紅麗;;壯醫(yī)藥線點(diǎn)灸療法治療蕁麻疹技術(shù)[N];民族醫(yī)藥報(bào);2012年

相關(guān)碩士學(xué)位論文 前1條

1 陳鳳;藥線灸結(jié)合電針、刺絡(luò)拔罐治療急性期帶狀皰疹的臨床研究[D];廣州中醫(yī)藥大學(xué);2014年

，

本文編號(hào)：2493386