【摘要】：目的：研究輸卵管性不孕(tubal factor infertility, TFI)常見的中醫(yī)證型及中醫(yī)體質(zhì)分布特點(diǎn),并探討本疾病中醫(yī)證型、中醫(yī)體質(zhì)與發(fā)病相關(guān)因素間的關(guān)系,中醫(yī)證型與體質(zhì)之間的相關(guān)性,為輸卵管性不孕的辨證及防治提供理論基礎(chǔ)。方法：收集2015年7月至2016年4月就診于廣州中醫(yī)藥大學(xué)一附院婦科病房及門診中診斷為輸卵管性不孕患者的臨床資料,包括：年齡、流產(chǎn)次數(shù)等一般資料、中醫(yī)證候、體質(zhì)判定相關(guān)情況等。并參照《中藥新藥臨床研究指導(dǎo)原則》、《中醫(yī)證候規(guī)范》、《中醫(yī)婦科學(xué)》及王琦教授的關(guān)于體質(zhì)九分法診斷標(biāo)準(zhǔn)對(duì)調(diào)查對(duì)象進(jìn)行中醫(yī)證型及體質(zhì)的辨證分型。并將獲得的原始數(shù)據(jù)錄入Excel進(jìn)行整理,選擇SPSS 20.0對(duì)數(shù)據(jù)進(jìn)行統(tǒng)計(jì)分析。結(jié)果：1.本次調(diào)查126例TFI患者中醫(yī)證型分布規(guī)律如下：氣滯血瘀型48.4%、腎虛血瘀型32.5%、痰瘀互結(jié)型11.1%、其它4.8%、濕熱瘀結(jié)型3.2%。2.本次調(diào)查126例TFI患者體質(zhì)分布為：陽虛質(zhì)(19.0%)、氣郁質(zhì)(18.3%)、血瘀質(zhì)(15.1%)、氣虛質(zhì)(12.7%)、平和質(zhì)(11.9%)、痰濕質(zhì)(7.9%)、陰虛質(zhì)(7.9%)、濕熱質(zhì)(7.2%)。3.本次調(diào)查126例TFI流產(chǎn)史患者中腎虛血瘀(44.6%)氣滯血瘀(33.9%)痰瘀互結(jié)(16.1%)濕熱瘀結(jié)(3.6%)其它(1.8%)。盆腔炎患者中氣滯血瘀(43.3%)腎虛血瘀(23.3%)痰瘀互結(jié)(20%)濕熱瘀結(jié)(6.7%)、其它(6.7%)。UU感染患者中氣滯血瘀(52.2%)腎虛血瘀(30.4%)痰瘀互結(jié)(17.4%)。CT感染患者中氣滯血瘀(37.5%)腎虛血瘀(37.5%)痰瘀互結(jié)(12.5%)其它(12.5%)。4.本次調(diào)查126例輸卵管性不孕患者證型判定為氣滯血瘀患者中陽虛質(zhì)占29.5%,氣郁質(zhì)占19.7%,血瘀質(zhì)占14.8%；判定為腎虛血瘀患者中陰虛質(zhì)占19.5%,血瘀質(zhì)占14.6%,陽虛質(zhì)占12.2%。結(jié)論：1.輸卵管性不孕患者主要以陽虛質(zhì)、氣郁質(zhì)、血瘀質(zhì)三種體質(zhì)類型分布為主。2.輸卵管性不孕患者中以氣滯血瘀及腎虛血瘀兩種中醫(yī)證型最常見。3.中醫(yī)證型分布與流產(chǎn)次數(shù)、患者年齡有相關(guān)性,與是否合并盆腔炎、是否有支原體或衣原體感染之間無相關(guān)性。中醫(yī)體質(zhì)分布與流產(chǎn)次數(shù)、年齡、是否合并盆腔炎、是否有支原體或衣原體感染之間無相關(guān)性。4.輸卵管性不孕患者中體質(zhì)分布與中醫(yī)證型之間存在相關(guān)性,兩者相互影響。其中,氣滯血瘀證中以陽虛質(zhì)、氣郁質(zhì)、血瘀質(zhì)三種體質(zhì)分布為主；腎虛血瘀型以陰虛質(zhì)、血瘀質(zhì)、陽虛質(zhì)三種體質(zhì)分布為主。
[Abstract]:Objective: to study the common TCM syndrome types and the distribution characteristics of TCM physique in tubal infertile (tubal factor infertility, TFI), and to explore the relationship between TCM syndrome type, TCM physique and related factors, and the correlation between TCM syndrome type and physique. It provides a theoretical basis for syndrome differentiation and prevention and treatment of tubal sterility. Methods: from July 2015 to April 2016, the clinical data of patients diagnosed as tubal infertile in gynecological ward and outpatient department of a affiliated Hospital of Guangzhou University of traditional Chinese Medicine were collected, including general data such as age, number of miscarriages, TCM syndromes. Physique judgment related situation, etc. Referring to the guiding principles of Clinical Research of New drugs of traditional Chinese Medicine, Standard of TCM Syndrome, Gynecology of traditional Chinese Medicine and Professor Wang Qi's diagnostic criteria of nine points of physique, the syndrome types of TCM and physique were classified according to the diagnostic criteria of nine points of physique. The original data are input into Excel for collation, and SPSS 20.0 is selected for statistical analysis. Results: 1. The distribution of TCM syndromes in 126 patients with TFI was as follows: qi stagnation and blood stasis type 48.4%, kidney deficiency and blood stasis type 32.5%, phlegm and blood stasis type 11.1%, other 4.8%, dampness-heat stasis type 3.2%. The physique distribution of 126 patients with TFI was yang deficiency (19.0%), qi stagnation (18.3%), blood stasis (15.1%), qi deficiency (12.7%), peace (11.9%) and phlegm dampness (7.9%). Yin deficiency (7.9%), dampness and heat (7.2%). 3. In this investigation, kidney deficiency and blood stasis (44.6%), qi stagnation and blood stasis (33.9%), phlegm and blood stasis (16.1%), dampness-heat stasis (3.6%) and others (1.8%) were investigated in 126 patients with TFI abortion history. In patients with pelvic inflammation, qi stagnation and blood stasis (43.3%), kidney deficiency and blood stasis (23.3%), phlegm and blood stasis (20%), dampness and heat stasis (6.7%), The other (6.7%). In patients with UU infection, qi stagnation and blood stasis (52.2%), kidney deficiency and blood stasis (30.4%), phlegm and blood stasis (17.4%), qi stagnation and blood stasis (37.5%), kidney deficiency and blood stasis (37.5%) in patients with CT infection. %) phlegm and blood stasis (12.5%) others (12.5%). 4. In 126 patients with tubal sterility, the syndrome types were as follows: Yang deficiency (29.5%), qi stagnation (19.7%) and blood stasis (14.8%). In the patients with kidney deficiency and blood stasis, yin deficiency, blood stasis and yang deficiency accounted for 19.5%, 14.6% and 12.2% respectively. Conclusion: 1. The main physical types of tubal infertile patients were yang deficiency, qi stagnation and blood stasis. 2. Among the patients with tubal sterility, qi stagnation and blood stasis and kidney deficiency and blood stasis are the most common TCM syndromes. The distribution of TCM syndromes was correlated with the number of miscarriages and the age of patients, and there was no correlation between the distribution of TCM syndromes and the number of miscarriages and the age of patients, and whether there was mycoplasma or chlamydia infection or not. There was no correlation between the physical distribution of traditional Chinese medicine and the number of miscarriages, age, pelvic inflammation, mycoplasma or chlamydia infection. 4. There is a correlation between physique distribution and TCM syndrome type in tubal infertile patients, and the two influence each other. Among them, yang deficiency, qi stagnation and blood stasis were the main physique distribution in qi stagnation and blood stasis syndrome, and yin deficiency, blood stasis and yang deficiency were the main types of kidney deficiency and blood stasis.
【學(xué)位授予單位】：廣州中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2016
【分類號(hào)】：R271.14

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