【摘要】：目的:通過對(duì)半夏秫米湯加減治療濕熱擾神型失眠臨床療效指標(biāo)的觀察、統(tǒng)計(jì)分析,客觀地評(píng)價(jià)半夏秫米湯加減治療濕熱擾神型失眠的臨床療效,對(duì)比中藥與西藥治療失眠的優(yōu)劣,為推廣臨床多用中醫(yī)經(jīng)方、驗(yàn)方加減治療疾病奠定基礎(chǔ)。材料與方法:本研究選取60例符合試驗(yàn)納入標(biāo)準(zhǔn)的患者,運(yùn)用隨機(jī)數(shù)字表法平均分為治療組和對(duì)照組,每組各30例。其中治療組予以半夏秫米湯加減治療,對(duì)照組予以佐匹克隆片治療,7天為一個(gè)療程,共3個(gè)療程,并保證全程用藥。統(tǒng)計(jì)治療前后各患者匹茲堡睡眠質(zhì)量指數(shù)(PSQI)積分和中醫(yī)證候積分變化情況以及兩組用藥總有效率之間差異,并加以分析。結(jié)果:(1)治療組和對(duì)照組治療前后匹茲堡睡眠質(zhì)量指數(shù)(PSQI)進(jìn)行組內(nèi)比較,統(tǒng)計(jì)分析結(jié)果:P0.05,有顯著性差異;治療組和對(duì)照組兩組之間進(jìn)行比較,統(tǒng)計(jì)分析結(jié)果:P0.05,無顯著性差異,無統(tǒng)計(jì)學(xué)意義。(2)治療組和對(duì)照組治療前后中醫(yī)證候積分進(jìn)行組內(nèi)比較,統(tǒng)計(jì)分析結(jié)果:P0.05,有顯著性差異;治療組和對(duì)照組兩組之間進(jìn)行比較,統(tǒng)計(jì)分析結(jié)果:P0.05,有顯著性差異,具有統(tǒng)計(jì)學(xué)意義。(3)治療組用藥總有效率為86.7%,對(duì)照組用藥總有效率為83.3%,治療組與對(duì)照組總有效率大致相同,且統(tǒng)計(jì)分析結(jié)果:P0.05,無顯著性差異,不具有統(tǒng)計(jì)學(xué)意義。結(jié)論:半夏秫米湯加減治療濕熱擾神型失眠有明確療效,患者PSQI積分、中醫(yī)證候積分均能夠改善,且對(duì)于中醫(yī)證候改善優(yōu)于西藥佐匹克隆,有一定的臨床推廣價(jià)值。以傳統(tǒng)經(jīng)方、驗(yàn)方進(jìn)行加減化裁治療疾病,能夠在確保一定治療效果的基礎(chǔ)上更加優(yōu)化治療方案,更好的對(duì)患者進(jìn)行治療,提高臨床療效,降低臨床風(fēng)險(xiǎn)。
[Abstract]:Objective: to evaluate objectively the clinical efficacy of Banxia sorghum rice decoction in the treatment of dampness-heat disturbance insomnia by observing and statistical analysis of the clinical curative effect of adding and decreasing Banxia sorghum rice decoction on damp-heat disturbing insomnia, and to evaluate objectively the clinical curative effect of Banxia sorghum rice decoction on damp-heat disturbance insomnia. To compare the advantages and disadvantages of traditional Chinese medicine (TCM) and western medicine in the treatment of insomnia, to lay a foundation for the promotion of clinical multi-use TCM prescriptions and the addition and subtractive treatment of diseases. Materials and methods: 60 patients were randomly divided into two groups: treatment group (n = 30) and control group (n = 30). The treatment group was treated with Banxia sorghum Millet decoction and the control group was treated with zopiclone tablets. The treatment group was treated with Zopiclone tablet for 7 days for a total of 3 courses, and the whole course of medication was guaranteed. The changes of Pittsburgh sleep quality index (PSQI) score and TCM syndrome score before and after treatment and the difference of total effective rate between the two groups were analyzed and analyzed. Results: (1) the Pittsburgh sleep quality index (PSQI) in the treatment group was compared with that in the control group before and after treatment. The statistical analysis showed that there was a significant difference between the treatment group and the control group (P 0.05). The results showed that there was no significant difference between the treatment group and the control group. (2) the TCM syndrome score of the treatment group was compared with that of the control group before and after treatment, and there was no significant difference between the treatment group and the control group. Statistical analysis results: P 0.05, there is a significant difference; (3) the total effective rate was 86.7% in the treatment group and 83.3% in the control group, and the total effective rate in the control group was 83.3%, and the total effective rate was 86.7% in the treatment group and 83.3% in the control group, the statistical analysis showed that there was significant difference between the treatment group and the control group. The total effective rate of the treatment group was the same as that of the control group, and the result of statistical analysis: P 0.05, there was no significant difference between the treatment group and the control group. Conclusion: Banxia sorghum rice decoction has definite curative effect in the treatment of dampness-heat disturbance insomnia. The PSQI score and TCM syndrome integral can be improved, and the improvement of TCM syndrome is better than that of Zopicone, which has a certain clinical value. The traditional prescription and the traditional prescription can optimize the treatment scheme, improve the clinical efficacy and reduce the clinical risk on the basis of ensuring a certain therapeutic effect on the basis of the treatment of the disease by the traditional prescription and the verification prescription.
【學(xué)位授予單位】：遼寧中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2016
【分類號(hào)】：R256.23
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本文編號(hào)：2468428