本文選題：乳腺癌 + 解建國　； 參考：《大連醫(yī)科大學(xué)》2016年碩士論文

【摘要】：背景:乳腺癌是現(xiàn)代女性高發(fā)的惡性腫瘤,隨著科技進(jìn)步時(shí)代發(fā)展生活節(jié)奏的加快,都市女性面臨的社會工作家庭諸多問題所承受的的壓力也比以前變得復(fù)雜多樣,近年乳腺癌發(fā)病率也有了明顯的上升趨勢,其發(fā)病率及死亡率已居我國女性惡性腫瘤之首[1],其中在我國北京、上海、深圳等沿海發(fā)達(dá)地區(qū)的發(fā)病率明顯高于內(nèi)陸偏遠(yuǎn)貧困地區(qū)�；熥鳛橹委熌[瘤疾病的重要手段之一,雖然在控制局部復(fù)發(fā)和全身轉(zhuǎn)移方面效果顯著,然由于化療藥物的低選擇性,往往對正常細(xì)胞造成誤殺,抑制了機(jī)體的免疫功能,常表現(xiàn)為惡心嘔吐、食欲不振、疲乏倦怠、煩躁失眠、毛發(fā)脫落、臟器功能損傷、腹痛、腹瀉或便秘等毒副反應(yīng),常常使術(shù)后本已虛弱的患者心力交瘁、受盡折磨,嚴(yán)重的甚至被迫放棄治療中斷化療。為了減輕這些毒副反應(yīng),使病人順利完成全部治療,西醫(yī)采取了一系列相應(yīng)措施以期緩解化療所產(chǎn)生的臨床癥狀,然效果皆不盡人意,有的甚至進(jìn)一步損傷肝腎等臟器,帶來新的毒副反應(yīng)。尋找行之有效的治療方法,降低乳腺癌化療的毒副反應(yīng),成為臨床關(guān)注探索的焦點(diǎn)。為了解決這些問題,近年一些臨床醫(yī)生漸漸開始嘗試在乳腺癌化療過程中配合相應(yīng)的中藥治療,以緩解化療藥物的毒副作用,并取得了較好的治療效果。由此,中醫(yī)藥在治療乳腺癌化療毒副反應(yīng)中,以其綠色有效無損害的顯著優(yōu)勢逐漸的受到臨床醫(yī)生和患者的青睞,如何使其更廣泛的應(yīng)用于臨床成為現(xiàn)代醫(yī)學(xué)探索專研的熱點(diǎn)。目的:解建國教授從醫(yī)四十余載,臨證經(jīng)驗(yàn)豐富,對乳腺癌化療所引起的一系列副反應(yīng)的治療更是有著獨(dú)到的見解。本文將就解教授治療乳腺癌化療副反應(yīng)的學(xué)術(shù)特點(diǎn)、用藥思路加以介紹闡述,希望可以為臨床治療乳腺癌化療副作用提供新方法,并為將來中醫(yī)藥在降低腫瘤對化療藥物的耐藥性及促進(jìn)術(shù)后恢復(fù)、控制腫瘤發(fā)展、復(fù)發(fā)轉(zhuǎn)移等的治療上提供新思路。研究方法:經(jīng)過近3年的跟師學(xué)習(xí),結(jié)合臨床典型病案加以剖析體會,整理相關(guān)資料,查閱國內(nèi)外文獻(xiàn),將解師治療乳腺癌化療副反應(yīng)的辨證思路及用藥特點(diǎn)加以歸納總結(jié)。結(jié)果:根據(jù)乳腺癌患者化療所產(chǎn)生副反應(yīng)的不同程度及特點(diǎn),采用中藥湯劑,靈活加減,辨證論治,有效的緩解了乳腺癌化療引起的惡心、嘔吐、腹瀉或便秘、疲乏、失眠等毒副反應(yīng),改善食欲不振,激發(fā)自身免疫力,明顯提高了病人的生活品質(zhì),延長了生存期。結(jié)論:解師自擬乳腺癌化療副反應(yīng)經(jīng)驗(yàn)方有效緩解了乳腺癌患者化療所產(chǎn)生毒副反應(yīng),減輕了病人痛苦,使其順利完成全部化療,在臨床中取得了顯著效果,其治療經(jīng)驗(yàn)值得我們學(xué)習(xí)研究及傳承應(yīng)用。
[Abstract]:Background: breast cancer is a malignant tumor with a high incidence among modern women. With the rapid pace of development of life in the era of scientific and technological progress, the pressure on urban women's social work and family problems has become more complex and diverse than before. In recent years, the incidence of breast cancer has also increased obviously. The incidence and mortality of breast cancer have been ranked first among the female malignant tumors in China. The incidence of breast cancer in developed coastal areas such as Beijing, Shanghai, Shenzhen and so on is obviously higher than that in remote and poor inland areas. Chemotherapy is one of the important methods in the treatment of tumor diseases. Although it has a remarkable effect in controlling local recurrence and systemic metastasis, however, because of the low selectivity of chemotherapeutic drugs, it often causes manslaughter to normal cells and inhibits the immune function of the body. Often manifested as nausea, vomiting, loss of appetite, fatigue, restlessness, insomnia, hair loss, organ function damage, abdominal pain, diarrhea or constipation and other toxic side effects, often make the patient who is already weak after the operation, exhausted and tormented, Severe even forced to abandon treatment to interrupt chemotherapy. In order to alleviate these side effects and make the patients complete all the treatment successfully, Western medicine took a series of corresponding measures to alleviate the clinical symptoms produced by chemotherapy. However, the effect was not satisfactory, and some even further damaged the organs such as liver and kidney. Bring new side effects. It has become the focus of clinical exploration to find effective treatment methods to reduce the side effects of breast cancer chemotherapy. In order to solve these problems, in recent years, some clinicians began to try to cooperate with traditional Chinese medicine in the process of breast cancer chemotherapy, in order to alleviate the toxic and side effects of chemotherapy drugs, and achieved a good therapeutic effect. As a result, traditional Chinese medicine in the treatment of breast cancer chemotherapy side effects, because of its significant advantage of green effectiveness and no damage gradually favored by clinicians and patients, how to make its wider application in clinical practice has become a hot spot of modern medical exploration. Objective: professor Xie Jianguo has been in medicine for more than 40 years and has rich clinical experience. He has a unique opinion on the treatment of a series of side effects caused by chemotherapy of breast cancer. This article will introduce Professor Jie's academic characteristics of side effects of chemotherapy for breast cancer and the thinking of drug use in order to provide a new method for the treatment of side effects of chemotherapy in breast cancer. It also provides new ideas for the treatment of tumor resistance to chemotherapeutic drugs, promoting postoperative recovery, controlling tumor development, recurrence and metastasis in the future. Methods: after nearly 3 years' study, combined with the clinical typical medical records, the author analyzed and analyzed the relevant materials, consulted the domestic and foreign literature, and summed up the syndrome differentiation thinking and the characteristics of drug use in the treatment of the side effects of chemotherapy in breast cancer. Results: according to the different degree and characteristics of the side effects caused by chemotherapy in breast cancer patients, traditional Chinese medicine decoction, flexible addition and subtraction, differentiation of symptoms and signs were used to effectively relieve nausea, vomiting, diarrhea or constipation caused by chemotherapy of breast cancer, and fatigue. The side effects, such as insomnia, improve anorexia, stimulate immunity, improve the patient's quality of life and prolong the life span. Conclusion: the experience prescription of self-made chemotherapy side effects of breast cancer can effectively alleviate the side effects of chemotherapy in patients with breast cancer, alleviate the pain of patients, make it complete all chemotherapy smoothly, and achieve remarkable results in clinical practice. Its therapeutic experience is worth studying and inheriting application.
【學(xué)位授予單位】：大連醫(yī)科大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2016
【分類號】：R249;R273

【參考文獻(xiàn)】

相關(guān)期刊論文 前10條

1 顏莉芳;;艾灸足三里穴治療化療后遲發(fā)性嘔吐46例[J];內(nèi)蒙古中醫(yī)藥;2014年14期

2 申翔;丘平;;穴位貼敷療法治療乳腺癌化療后胃腸道反應(yīng)60例[J];云南中醫(yī)中藥雜志;2012年08期

3 王淼;曾柏榮;;中醫(yī)藥防治化療所致惡心嘔吐的研究進(jìn)展[J];湖南中醫(yī)雜志;2012年04期

4 王齊輝;;穴位注射配合耳穴貼壓降低惡性膠質(zhì)瘤切除術(shù)后化療引起的惡心嘔吐的護(hù)理體會[J];山西醫(yī)藥雜志(下半月刊);2012年06期

5 鄭麗萍;沈敏鶴;阮善明;李夢婷;林紅;;吳良村臨證治療乳腺癌經(jīng)驗(yàn)[J];四川中醫(yī);2011年08期

6 李麗;田菲;;乳腺癌術(shù)后康復(fù)期的辨治[J];山西中醫(yī);2011年07期

7 祝東升;趙立娜;鐘馨;王志堅(jiān);;益氣生血湯防治乳腺癌化療期間骨髓抑制35例[J];中醫(yī)雜志;2011年02期

8 李娜;孫一予;李小江;;賈英杰教授治療化療后脫發(fā)經(jīng)驗(yàn)介紹[J];現(xiàn)代中西醫(yī)結(jié)合雜志;2010年21期

9 姚德蛟;;健脾和胃固腎法防治化療嘔吐的認(rèn)識[J];陜西中醫(yī);2009年06期

10 池慧珍;林勝友;;中醫(yī)中藥在乳腺癌化療中的研究進(jìn)展[J];陜西中醫(yī)學(xué)院學(xué)報(bào);2009年02期

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