【摘要】：目的探討腫瘤專科醫(yī)院Ⅰ類切口手術(shù)圍術(shù)期預防使用抗菌藥物的干預效果,以降低手術(shù)切口感染的發(fā)生,提高臨床合理使用抗菌藥物水平。方法回顧性分析2011年9月-2012年8月腫瘤外科Ⅰ類切口手術(shù)患者240例,分為非干預組和干預組,各120例,根據(jù)抗菌藥物合理應(yīng)用評價標準,調(diào)查分析抗菌藥物預防性應(yīng)用情況,數(shù)據(jù)采用SPSS 13.0軟件進行統(tǒng)計分析。結(jié)果干預組患者圍手術(shù)期抗菌藥物使用率及合理應(yīng)用率分別為4.17%及96.67%,非干預組患者分別為35.83%及67.50%,兩組比較差異有統(tǒng)計學意義(P0.05);非干預組患者圍手術(shù)期抗菌藥物不合理用藥無適應(yīng)證占30.00%、藥物選擇不當占26.67%、用量不當占6.67%、用藥時機不當16.67%,干預組患者不合理用藥為無適應(yīng)證占2.50%、藥物選擇不當占0.83%,干預后抗菌藥物的合理性限制顯著提高。結(jié)論醫(yī)院采用的干預措施,有效提高了Ⅰ類切口手術(shù)圍術(shù)期抗菌藥物的合理使用。
[Abstract]:Objective to investigate the intervention effect of preventing the use of antibiotics during perioperative operation of class I incision in tumor hospital in order to reduce the occurrence of incision infection and improve the level of rational use of antibiotics in clinic. Methods from September 2011 to August 2012, 240 patients undergoing class I incision surgery in tumor surgery were divided into non-intervention group (n = 120) and intervention group (n = 120). According to the evaluation criteria of rational use of antibiotics, the preventive use of antibiotics was investigated and analyzed. The data were statistically analyzed by SPSS 13.0 software. Results the utilization rate and rational use rate of antibiotics in the intervention group and the non-intervention group were 4.17% and 96.67% respectively, and 35.83% and 67.50% in the non-intervention group, respectively. there was significant difference between the two groups (P 0.05). In the non-intervention group, the irrational use of antibiotics accounted for 30.00%, the improper drug selection accounted for 26.67%, the improper dosage was 6.67%, and the timing was 16.67%. The unreasonable use of antibiotics in the intervention group accounted for 2.50% of the patients without indication, and the improper drug selection accounted for 0.83%. The reasonable limitation of antibiotics increased significantly after intervention. Conclusion the intervention measures adopted in hospital can effectively improve the rational use of antibiotics during perioperative period of class I incision surgery.
【作者單位】： 南通大學附屬腫瘤醫(yī)院藥學部;
【基金】：江蘇省南通科技局基金資助項目(HS12945)
【分類號】：R969.3

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