不同廠家青霉素V鉀片的體外溶出曲線比較
發(fā)布時間：2019-06-21 00:33
【摘要】：本文研究了國內(nèi)6個廠家生產(chǎn)的青霉素V鉀片在磷酸鹽緩沖溶液(pH 6.8)、醋酸鹽緩沖溶液(pH 4.5)以及0.01 mol/L鹽酸溶液(pH 1.0)的溶出度,并采用相似f_2因子法,以原研廠家的青霉素V鉀片為參比制劑進(jìn)行了溶出曲線相似度的比較,為臨床使用青霉素V鉀片提供更好的參考依據(jù)。
[Abstract]:In this paper, the dissolution of penicillin V potassium tablets produced by six domestic manufacturers in phosphate buffer solution (pH 6.8), acetate buffer solution (pH 4.5) and 0.01mol/L hydrochloric acid solution (pH 1.0) was studied. The similarity of dissolution curve was compared by using similar f 鈮，
本文編號：2503649
[Abstract]:In this paper, the dissolution of penicillin V potassium tablets produced by six domestic manufacturers in phosphate buffer solution (pH 6.8), acetate buffer solution (pH 4.5) and 0.01mol/L hydrochloric acid solution (pH 1.0) was studied. The similarity of dissolution curve was compared by using similar f 鈮，
本文編號：2503649
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