我院住院患者質(zhì)子泵抑制劑使用情況調(diào)查及不合理用藥分析
發(fā)布時(shí)間:2019-01-17 07:48
【摘要】:正質(zhì)子泵抑制劑(proton pump inhibitors,PPI)通過阻礙胃壁細(xì)胞H+-K+-ATP酶發(fā)揮抑制胃酸分泌的作用,是目前最有效的胃酸分泌抑制劑和抗?jié)兯幬铩3S糜谑改c潰瘍、胃潰瘍、反流性食管炎、根除幽門螺桿菌(HP)和卓艾綜合征(胃泌素瘤)等病,是治療消化性潰瘍病的良藥。但是PPI作為強(qiáng)效抑酸藥,會(huì)降低胃液中H+濃度,促使胃液pH升高,造成胃內(nèi)環(huán)境的明顯改變,影響某
[Abstract]:Positive proton pump inhibitor (proton pump inhibitors,PPI) inhibits gastric acid secretion by blocking H-K-ATP enzyme in gastric parietal cells and is the most effective inhibitor and anti-ulcer drug. It is commonly used in duodenal ulcer, gastric ulcer, reflux esophagitis, eradication of Helicobacter pylori (HP) and Zhuoai syndrome (gastrinoma) and is a good medicine for peptic ulcer. However, PPI, as a powerful acid suppressant, can reduce H concentration in gastric juice, promote the increase of pH in gastric juice, and cause obvious changes in gastric environment, which affects a certain amount of H in gastric juice.
【作者單位】: 中鐵十七局集團(tuán)有限公司中心醫(yī)院藥劑科;山西醫(yī)科大學(xué)第一醫(yī)院護(hù)理部;山西醫(yī)科大學(xué)第一醫(yī)院老年病科;
【分類號(hào)】:R969
本文編號(hào):2409782
[Abstract]:Positive proton pump inhibitor (proton pump inhibitors,PPI) inhibits gastric acid secretion by blocking H-K-ATP enzyme in gastric parietal cells and is the most effective inhibitor and anti-ulcer drug. It is commonly used in duodenal ulcer, gastric ulcer, reflux esophagitis, eradication of Helicobacter pylori (HP) and Zhuoai syndrome (gastrinoma) and is a good medicine for peptic ulcer. However, PPI, as a powerful acid suppressant, can reduce H concentration in gastric juice, promote the increase of pH in gastric juice, and cause obvious changes in gastric environment, which affects a certain amount of H in gastric juice.
【作者單位】: 中鐵十七局集團(tuán)有限公司中心醫(yī)院藥劑科;山西醫(yī)科大學(xué)第一醫(yī)院護(hù)理部;山西醫(yī)科大學(xué)第一醫(yī)院老年病科;
【分類號(hào)】:R969
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