沐舒坦圍手術(shù)期肺保護(hù)機(jī)制及應(yīng)用策略
發(fā)布時(shí)間:2018-08-18 19:00
【摘要】:沐舒坦的藥理作用機(jī)制包括分解氣道黏液蛋白多糖、促進(jìn)纖毛上皮再生和纖毛正常功能恢復(fù)、刺激肺泡Ⅱ型細(xì)胞合成及分泌肺泡表面活性物質(zhì)、抗氧化作用、清除自由基、協(xié)同抗生素作用等。沐舒坦臨床常用于圍手術(shù)期肺功能的保護(hù)。在臨床使用中,常有不同的應(yīng)用策略:可依據(jù)其療效的劑量依賴(lài)性,小劑量用于化痰,大劑量用于肺保護(hù);給藥途徑分為靜滴、霧化、氣管滴入等,適合不同病情的需要;可通過(guò)不同時(shí)機(jī)(術(shù)前、術(shù)中、術(shù)后)給藥進(jìn)行肺保護(hù);可應(yīng)用于嬰幼兒、老年人、成人等不同年齡階段人群;在多學(xué)科手術(shù)的圍手術(shù)期進(jìn)行肺保護(hù)。本文對(duì)沐舒坦圍手術(shù)期肺保護(hù)機(jī)制及應(yīng)用方法系統(tǒng)、全面進(jìn)行了綜述,以指導(dǎo)應(yīng)用。
[Abstract]:The pharmacological mechanisms of ambroxol include the decomposition of airway mucin proteoglycan, promoting the regeneration of cilia epithelium and the recovery of normal function of cilia, stimulating the synthesis and secretion of alveolar surfactant by alveolar type 鈪,
本文編號(hào):2190378
[Abstract]:The pharmacological mechanisms of ambroxol include the decomposition of airway mucin proteoglycan, promoting the regeneration of cilia epithelium and the recovery of normal function of cilia, stimulating the synthesis and secretion of alveolar surfactant by alveolar type 鈪,
本文編號(hào):2190378
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