發(fā)布時(shí)間：2018-05-30 06:10

  本文選題：復(fù)合菌-荔枝多酚 + 抗腹瀉效果　； 參考：《食品工業(yè)科技》2017年10期

【摘要】：為研究復(fù)合菌-荔枝多酚對(duì)小鼠抗腹瀉效果、生長(zhǎng)性能及抗氧化的影響,選用96只體重為18~22 g的SPF級(jí)昆明小鼠,隨機(jī)分為8個(gè)處理組:正常組、模型組、陽(yáng)性對(duì)照組、嗜酸乳桿菌組(Lactobacillus acidophilus)、丁酸梭菌組(Clostridium butyricum)、荔枝多酚組、復(fù)合菌組(Lactobacillus acidophilus和Clostridium butyricum)、復(fù)合菌-荔枝多酚組,實(shí)驗(yàn)周期為14 d。于實(shí)驗(yàn)第1~14 d分別進(jìn)行預(yù)防性及治療性給藥(除正常組和模型組),定期測(cè)所有小鼠體重和采食量,實(shí)驗(yàn)第10 d利用蓖麻油灌胃法制備小鼠腹瀉模型觀察腹瀉指標(biāo),實(shí)驗(yàn)第14 d,對(duì)各組小鼠血清的SOD和GSH-Px及CAT進(jìn)行測(cè)定。結(jié)果表明:造模當(dāng)天,模型組的體重變化最明顯,腹瀉最嚴(yán)重,復(fù)合菌-荔枝多酚組抑制小鼠的腹瀉效果最好;抗氧化指標(biāo)顯示,復(fù)合菌組和荔枝多酚組SOD、GSH-Px及CAT含量均顯著高于模型組(p0.05),而復(fù)合菌-荔枝多酚組GSH-Px及CAT含量顯著高于模型組(p0.05)。本研究表明,對(duì)小鼠蓖麻油腹瀉模型,復(fù)合菌-荔枝多酚表現(xiàn)出明顯的抗腹瀉和抗氧化效果。
[Abstract]:In order to study the effects of compound bacteria lychee polyphenols on anti-diarrhea, growth performance and antioxidation in mice, 96 Kunming mice of SPF grade, weighing 1822 g, were randomly divided into 8 groups: normal group, model group and positive control group. Lactobacillus acidophilus, Clostridium butyricumum, litchi polyphenols, compound bacteria Lactobacillus acidophilus and Clostridium butyricumum, compound bacillus and lychee polyphenols, the experimental period was 14 days. Preventive and therapeutic administration were performed on the 1st day of the experiment (except the normal group and the model group). The body weight and intake of all mice were measured regularly. On the 10th day of the experiment, the diarrhea index of the diarrhea model of mice was prepared by the method of castor oil gastric perfusion. On the 14th day, the serum SOD, GSH-Px and CAT of each group were determined. The results showed that the weight of the model group was the most obvious and diarrhea was the most serious on the day of model making, and the anti-oxidation index showed that the compound bacterial-lychee polyphenols group had the best effect on inhibiting diarrhea in mice. The contents of GSH-Px and CAT in compound bacteria group and lychee polyphenol group were significantly higher than those in model group, while the contents of GSH-Px and CAT in compound bacteria group and lychee polyphenol group were significantly higher than those in model group. The results showed that the compound bacteria lychee polyphenols showed obvious anti-diarrhea and anti-oxidation effects on castor oil diarrhea model in mice.
【作者單位】： 華中農(nóng)業(yè)大學(xué);廣東省農(nóng)業(yè)科學(xué)院動(dòng)物衛(wèi)生研究所;
【基金】：廣東省科技計(jì)劃項(xiàng)目(2015A020209080) 廣州市科技計(jì)劃項(xiàng)目(201604020138)
【分類號(hào)】：R965
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本文編號(hào)：1954225